DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a2 and CYP705A23

DIOPT Version :9

Sequence 1:	NP_523628.1	Gene:	Cyp6a2 / 35587	FlyBaseID:	FBgn0000473	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_188649.1	Gene:	CYP705A23 / 821557	AraportID:	AT3G20140	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	111/549 - (20%)
Similarity:	208/549 - (37%)	Gaps:	120/549 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIYLLIAISSLLAYLYHRNFNYWNRRGVPHDA----PHPLYGNMVGFRK---NRVMHDFFYDYYN 61
            ||::|:.|..||.|..     ::.:..|..|.    |.||...::|...   :.:.|.......:
plant    13 LIFILLCILLLLCYPL-----FFKKPKVSQDGFGLPPSPLSLPIIGHLHLLFSNLTHKSLQKLSS 72

  Fly    62 KYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHL-------F 119
            ||.    |.:.....:.|..|:....:|..|......|.:.||      :.|:.:.|       |
plant    73 KYG----PLLYLRIFNVPIIFVSSASVAYEIFRGHDVNISFRG------NPPIEESLLVGSFGFF 127

  Fly   120 NLD-GKKWKDMRQRLTPTFTSGKM---------------------KFMFPTVIKVSEEFVKVITE 162
            ... |..||.|::.:.......:.                     |.|....:::.:|.:|:|.:
plant   128 TAPYGDYWKFMKKVMVTKLLGPQALQRSRGIRADALERFYMNLLDKAMKKESVEIGKETMKLIYD 192

  Fly   163 QVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVF-TDMRHGKLLTMF 226
            .:          .|.:|.|..::..|      |...:|..|::...:.:|:| .::.|..|..:.
plant   193 SI----------CKMIMGRNFSEENG------EAERVRGLVTESTALTKKIFMANVLHKPLKKLG 241

  Fly   227 VFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRN---DFMNLLI----ELKQKGRV 284
            :..|.|       .:|  ||...|..|: :...:...|....:   |.|.:|:    :...:.::
plant   242 ISLFKK-------EIM--DVSNSFDELL-ERFLVEHEEKLNEDQDMDMMGVLLAACRDKNAECKI 296

  Fly   285 TLDNGEVIEGMDIGELAAQVFV-FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE 348
            |.::            ...:|| ..|||.:||.....:.:.|:.....:.:::|.||.:|:...
plant   297 TRNH------------IKSLFVDLVVAGTDTSRHATQWTMAEIINKPKVLEKVREEIYSVVGRT- 348

  Fly   349 GQLTYES-IKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHR 412
             :|..|: :.::.||...:.|.|||:...|...|.|...:.|.|   ..:.:.|.:::.|.|..|
plant   349 -RLVQETDLPSLPYLQATVKEGLRLHPPGPLFARTAREGFSVGG---FYVPENTPLVVNAYAMMR 409

  Fly   413 DEDLYPNPETFDPERF--SPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRF--- 472
            |...:.:|..|.||||  |.::......::::|||.|.|.|.|:....:.....:..::..|
plant   410 DPGSWEDPNEFKPERFLGSGKEDEREHGLKYIPFGSGRRGCPGINLAYILVGTAIGVMVQCFDWK 474

  Fly   473 -----------RVSVCDTTEIPLKYSPMS 490
                       |.|:..|...|||..|::
plant   475 IKGNKVNMEEARGSLVLTMAHPLKCIPVA 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	102/513 (20%)
CYP705A23	NP_188649.1	p450	26..504	CDD:386267	105/536 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010