DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a2 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_523628.1	Gene:	Cyp6a2 / 35587	FlyBaseID:	FBgn0000473	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	434	Identity:	115/434 - (26%)
Similarity:	190/434 - (43%)	Gaps:	63/434 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQ----HLFNL 121
            |.:.|:.|.::|      |...||.|...:   ||:..|..:  .|......||.:    .|.:.
plant    89 NSHGKTFFIWIG------PLPTIVITNPEQ---IKEVFNKVN--DFEKASTFPLIRLLAGGLASY 142

  Fly   122 DGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFV----KVITEQVPAAQNGAVLEIKELMARF 182
            .|.||...|:.:.|.|...|:|.|.|.......|.|    |:.|::    ::...:::...:...
plant   143 KGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDK----ESPLEVDVWPWLVNM 203

  Fly   183 TTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPK----------LASRL 237
            |.|||...|||          |.::. ||::|  ...|:|..:...:|.|          ..|..
plant   204 TADVISHTAFG----------SSYKE-GQRIF--QLQGELAELIAQAFKKSYIPGSRFYPTKSNR 255

  Fly   238 RMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIE--GMDIGEL 300
            ||:.:..:|......:|:.....||......:|.:.:|:|         .|.|..:  ||.:.::
plant   256 RMKAIDREVDVILRGIVSKREKAREAGEPANDDLLGILLE---------SNSEESQGNGMSVEDV 311

  Fly   301 AAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQV 365
            ..:..:||.||.||:|..:.:.:..|:.:||.|.|.|.|:..||.| ..:...||:..:..:..:
plant   312 MKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQVLGE-NNKPDMESLNNLKVMTMI 375

  Fly   366 ISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFS 429
            .:|.||||..|..|:| .:|..:..|  :|.:..|.|:.:|.....||.:|: .:...|.||||.
plant   376 FNEVLRLYPPVAQLKR-VVNKEMKLG--ELTLPAGIQIYLPTILVQRDTELWGDDAADFKPERFR 437

  Fly   430 PE-KVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRF 472
            .. ..|.:..|.:.|||.|||.|||..|..::|::.:|.|:.:|
plant   438 DGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAKMAMALILQKF 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	115/434 (26%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	115/434 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810