Protein Alignment Cyp6a2 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_073789299.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 499
• Species: Danio rerio
• Alignment Length: 550
• Identity: 137/550 - (24%)
• Similarity: 242/550 - (44%)
• Gaps: 101/550 - (18%)

  Fly     1 MFVLIYLLIAI----SSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGF----RKNRVMHDFFY 57
            :::|.|||.|:    .:...|::..:..|.:..|.|.|  :.|.|::...    :..|.|:|...
Zfish     7 LYMLFYLLSAVFVVFLAYCLYIHQVHLKYDHIPGPPRD--NFLLGHIPTINRVTKSERHMNDLLL 69

  Fly    58 DYYNK----YRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDP-LTQH 117
            .:..|    ||.:.|.:| ...:|.|.|       .|.|::..           ....|| :.:.
Zfish    70 IWAEKYGPVYRLNSFHYV-IINVHCPEA-------TKTIMMSP-----------KYLKDPFIYKR 115

  Fly   118 LFNLDGKK--------------WKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQ 168
            ||.|.||:              |...|:.:.|.|:|..::.:..|..::||..:..:.|.   |.
Zfish   116 LFGLFGKRFLGYGLVTATDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEM---AI 177

  Fly   169 NGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTM---FVFSF 230
            |.....:.:|:...|.|:|...|||::.|..:...:.|    |:.......|.:|.:   |...|
Zfish   178 NKTPAVMHDLVNCVTLDIICKVAFGVDLNLFKQTDNPF----QQAIEQCLQGMVLDLRDPFCKFF 238

  Fly   231 PK--------LASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRV--T 285
            ||        ..:.:.:|...|...|      |...|:...|:.. ||.:..:::..::.:|  |
Zfish   239 PKNWKAIQETKGATVLLRKTGEQWIQ------NRKTAVEIGEDVP-NDILTQILKTAKEEKVNNT 296

  Fly   286 LDNGEVIEGMDIGELAAQVFV-FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEG 349
            .|:.::::.          || |::||.||:::.:|:.:.||.::.:|..|.:.|:..||..:.
Zfish   297 KDHEQMLDN----------FVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGTKR- 350

  Fly   350 QLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDE 414
            .::||.:...|||:||:.||||||...|...|....|.|:.|   :.|..|..||..:....|.|
Zfish   351 DISYEDLGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMVING---IKIPGGISVIFSSYVAQRLE 412

  Fly   415 DLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDT 479
            ..:.:|..||||||:..  |.:....:.||..|||:|:|..|.||:|::.||:::.||..|:...
Zfish   413 KHFKDPLKFDPERFNVN--APKPYYCYYPFSLGPRSCLGQVFSQMEAKVVLAKLLQRFEFSLVPG 475

  Fly   480 TEIPLKYSPMSIVLGTV---GGIYLRVERI 506
            ....:|      .:||:   .|:...::::
Zfish   476 QSFEIK------DIGTLRPKSGVICNIKQL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	118/462 (26%)
cyp46a1.3	XP_073789299.1	None