Protein Alignment Cyp6a2 and Cyp4a31

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 539
• Identity: 134/539 - (24%)
• Similarity: 244/539 - (45%)
• Gaps: 89/539 - (16%)

  Fly     3 VLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSG 67
            |...||:.:.::..|| ||.:.....:..|....|..:|: ..|:.::.:.:......|
Mouse    24 VFCLLLLLVKAVQVYL-HRKWLLKALQQFPSPPFHWFFGH-EQFKGDQELQEIVSCIEN------ 80

  Fly    68 FP--FVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDP------------LTQHL 118
            ||  |..:::..|....:.|....|.||               ||.||            :...|
Mouse    81 FPSAFPRWFWGSKAYLTVYDPDYMKVIL---------------GRSDPKANGAYRLLAPWIGYGL 130

  Fly   119 FNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVP--AAQNGAVLEIKELMAR 181
            ..|:|:.|...|:.|||.|....:|    |.:|...:.::::.::..  |.|:.:: ||.:.::.
Mouse   131 LLLNGQSWFQHRKMLTPAFHYDILK----TYVKNMADSIRLMLDKWERLAGQDSSI-EIFQHISL 190

  Fly   182 FTTDVIGTCAF----GIECNTLRTPVSDFRTMGQKV--FTDMRHGKLLTMF-----VFSFPKLAS 235
            .|.|.:..|||    .::.:      .:::|..|.:  ..::.|.::..||     ::   ||:|
Mouse   191 MTLDTVMKCAFSHKGSVQVD------GNYKTYLQAIGDLNNLVHSRVRNMFHQNDTIY---KLSS 246

  Fly   236 RLRMR----MMPEDVHQFFMRLVNDTIALR-ERENFK---RNDFMNLLIELKQKGRVTLDNGEVI 292
            ..|:.    .:..|.....:::..|.:... |.||.|   |.||:::|:..:.:..
Mouse   247 NGRLSNQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENE--------- 302

  Fly   293 EGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIK 357
            :.|...:|.|:|..|.:.|.:|::|.:|:..|.||.:.:.|.|.|.|:|::|.: ...:|::.:.
Mouse   303 DSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGD-GSSITWDHLD 366

  Fly   358 AMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPET 422
            .:.|....|.|.||||..||.:.|:.......|  :...:.||.||.:.....|.:..::||||.
Mouse   367 QIPYTTMCIKEALRLYPPVPSIGRELSTSVTFP--DGCSLPKGVQVTLSIYGLHHNPKVWPNPEV 429

  Fly   423 FDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYS 487
            |||.||:|:  :.|.|..:|||..|.|||||.:|...:.::.:|..:.||.: :.|.|.:|:  |
Mouse   430 FDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFEL-LPDPTRVPM--S 489

  Fly   488 PMSIVLGTVGGIYLRVERI 506
            ....||.:..||||.::::
Mouse   490 LARFVLKSKNGIYLHLKKV 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	125/500 (25%)
Cyp4a31	NP_964002.2	p450	52..503	CDD:278495	125/503 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900