Protein Alignment Cyp6a2 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 408
• Identity: 113/408 - (27%)
• Similarity: 196/408 - (48%)
• Gaps: 57/408 - (13%)

  Fly   123 GKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVI-TEQVPAAQNGAV-LEIKELMARFTTD 185
            |.||...|:.|||.|....:|    ..:|:..:...:: .:.:..|..|:. |.:.|.::..|.|
Mouse   168 GDKWNRHRRMLTPAFHFNILK----PYVKIFNDSTNIMHAKWLRLASGGSTRLNMFENISLMTLD 228

  Fly   186 VIGTCAFGIECNTLRTP------VSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPE 244
            .:..|.|....|....|      :.:..|:..|     |:.:|| |.|        .|..|:.|:
Mouse   229 TLQKCVFSFNSNCQEKPSQYIAAILELSTLAVK-----RNEQLL-MHV--------DLLYRLTPD 279

  Fly   245 DVHQFF--MRLVND----TIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVI------EGMDI 297
            .: :|:  .|||:|    .|..|.|...|...  :.:|:.|.|.: |||..:|:      :|.::
Mouse   280 GM-RFYKACRLVHDFTDAVIQERRRTLLKHGG--DDIIKAKAKSK-TLDFIDVLLLTKDEDGKEL 340

  Fly   298 G--ELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE-GQLTYESIKAM 359
            .  ::.|:...|...|.:|::|.:|:.||.||::.:.|:|.|.|:|.:|.::: .::.::.:..:
Mouse   341 SDEDIRAEADTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELLRDRDPKEIEWDDLAQL 405

  Fly   360 TYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFD 424
            .:|...|.|:|||:..|..:.|....|..:|  :..:|.||...||.....|.:..::.:||.:|
Mouse   406 PFLTMCIKESLRLHPPVTMVSRCCTQDISLP--DGRIIPKGVICIINIFGTHHNPTVWRDPEVYD 468

  Fly   425 PERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM 489
            |.||.||.:.||..:.::||..|||||||..|...:.::.||..:.|||:       :|....|.
Mouse   469 PFRFDPENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRI-------LPDDKEPR 526

  Fly   490 ---SIVLGTVGGIYLRVE 504
               .::|...||::||||
Mouse   527 RKPELILRAEGGLWLRVE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	109/402 (27%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	109/404 (27%)