Protein Alignment Cyp6a2 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 610
• Identity: 122/610 - (20%)
• Similarity: 209/610 - (34%)
• Gaps: 213/610 - (34%)

  Fly     7 LLIAISSLLAYLYHRNFNYWN-RRGVPHD----APHPLYGNMVGFRKNRVMHDFFYDYYNKYRKS 66
            ||:|:|.||          |. |..:..|    .|.| .|:|
Zfish    24 LLLAVSRLL----------WEFRWSITRDRTCKLPLP-QGSM----------------------- 54

  Fly    67 GFPFVG--FYFLHKPAAF----------IVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQH-- 117
            |:|.||  |::|.:.::|          :..|.|....||:...       ..|.|...|.:|
Zfish    55 GWPLVGETFHWLFQGSSFHISRREKHGKVFKTHLLGKPLIRVTG-------AENIRKILLGEHTV 112

  Fly   118 -----------------LFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIK--VSEEFVKVITEQ 163
                             |.|..|...|..|:.|...|:.|.:: .:.|.::  |..|..|..||
Zfish   113 VCTQWPQSTRIILGPNTLVNSVGDLHKRKRKVLAKVFSRGALE-AYLTRLQDVVKSEIAKWCTE- 175

  Fly   164 VPAAQNGAVLEI----KELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLT 224
                 .|:| |:    |.|..|....|:    .|:.....:.      |...|.|..:.:.
Zfish   176 -----TGSV-EVYTAAKSLTFRIAVRVL----LGLHLEEQQI------TYLSKTFEQLMNN---- 220

  Fly   225 MFVFSFP------KLASRLRMRMMPEDVHQFFMRLVNDTIALRERENF-----------KRNDFM 272
              :||.|      .|...:|.|   |.:|....:::.:.:..::..::           :.||:.
Zfish   221 --LFSLPIDTPVSGLRKGIRAR---EILHSAMEKIIEEKLKKQQASDYCDAFDYMLSSARENDYE 280

  Fly   273 NLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLR 337
            ..:.|||:                    .|...:|  |...|::|..:..:.:|.::.|:.:|.|
Zfish   281 LTMQELKE--------------------TAVELIF--AAHSTTASASTSLIMQLLRHPDVSERAR 323

  Fly   338 NEIQT-------------------VLEE--------------------------QEGQ------- 350
            .|:::                   :.||                          :||:
Zfish   324 AELESEGLITDGHGHCRSRCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVP 388

  Fly   351 -LTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDE 414
             |:.|.:..::||:.|:.|.||....|....|..|..:.:.|::   |.||..|:......|...
Zfish   389 YLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTFELNGYQ---IPKGWSVMYSIRDTHETA 450

  Fly   415 DLYPNPETFDPERFSPEKVAAR-ESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCD 478
            :.|.|||.|||:||...:..:: |...::|||.|.|.|||.....:..:....:::     :..|
Zfish   451 EAYQNPELFDPDRFCVGREESKSERFSYVPFGGGVRRCIGRELALIVLKTLAVELL-----ATAD 510

  Fly   479 TTEIPLKYSPMSIV--LGTVGGIYL 501
            .|.....|..|..|  :..|.|:::
Zfish   511 CTLATQTYPRMQTVPIVHPVNGLHV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	108/540 (20%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	107/541 (20%)