Protein Alignment Cyp6a2 and LOC4577450

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_001230595.3
• Gene: LOC4577450 / 4577450
• VectorBaseID: AGAMI1_004862
• Length: 505
• Species: Anopheles gambiae
• Alignment Length: 538
• Identity: 124/538 - (23%)
• Similarity: 235/538 - (43%)
• Gaps: 90/538 - (16%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNR-----------RGVPHDAPHPLYGNMVGF-----RKN 49
            ||.:..|::.:..:|         ||::           :.:|....:||.|:...|     |..
Mosquito     1 MFFIPALILLLGLVL---------YWSKLSRKTSAQLFGKDIPGPRSYPLIGSAHLFLGSDERTF 56

  Fly    50 RVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPL 114
            .|:::.|..|.:.::.|..|        |....:.|..|.:..|..  |...|:..|:  |...|
Mosquito    57 SVINELFRKYGSFFKLSLGP--------KTFLCLSDPDLIQQALTS--SACQDKAFFY--RFMEL 109

  Fly   115 TQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVI-KVSEEFVKVITEQVPAAQNGAVLEIKEL 178
            ...|.:.....||..|:.|.|.|.. ::...|.::. :.||..|..:.::....|   ..:....
Mosquito   110 DYGLVSSRYTDWKLYRKSLNPAFNQ-RILISFISIFNRCSEVMVARMAKEADRRQ---PFDALHY 170

  Fly   179 MARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMP 243
            .|:.|.:::  ||..::.:....|.:.......:....:...:|..:.::|........|.|.|
Mosquito   171 TAQCTFEMV--CASSLKSDITHDPQAREACGAIEKMCAIMSSRLFNVLLYSDLLFTLTQRYREM- 232

  Fly   244 EDVHQFFMRLVN-------DTIALRERENFKRND---------FMNLLIELKQKGRVTLDNGEVI 292
            :.|.....|:||       :.::.:..||....|         |::.|:..::.||
Mosquito   233 QKVRATLGRVVNPILYGRREKLSKQRLENAHSEDEEHYRKPMVFLDQLLHTQRGGR--------- 288

  Fly   293 EGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIK 357
             .::|.|:...:.....||.||:::.:::.|..||.:.::|:|:..||.::.......|:||:|.
Mosquito   289 -DLEIQEIENHLNTIIGAGSETTANQVAFILLMLAMHPEVQERVYEEIVSIYGSAASDLSYETIS 352

  Fly   358 AMTYLNQVISETLRLYTLVPHLERKA-----LNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY 417
            |.|||.|||.||:|:|.:.|.:.|:.     |.|.:||        .|..::|.....||:::|:
Mosquito   353 AQTYLEQVIKETMRVYPVAPLIGRETIETVKLGDVIVP--------PGVTLLINILTVHRNKELW 409

  Fly   418 -PNPETFDPERFSPEKVAARES--VEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVS--VC 477
             .....|||:||.|.:..|::.  ..::|||.|||||||.|:|....:|.:.|::.::::|  :.
Mosquito   410 GERAHVFDPDRFDPAQYDAKKQHPFSYIPFGGGPRNCIGYRYGMFAMKIMVTQVLRKYQLSTPLT 474

  Fly   478 DTTEIPLKYSPMSIVLGT 495
            .|..:.|.:: :::.:||
Mosquito   475 PTDSLRLSFA-VTLKVGT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	108/454 (24%)
LOC4577450	XP_001230595.3	None