Protein Alignment Cyp6a2 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 482
• Identity: 115/482 - (23%)
• Similarity: 197/482 - (40%)
• Gaps: 83/482 - (17%)

  Fly    39 LYGN--MVGFRKNRVMHDFFYD---YYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFS 98
            |||:  ..|..::|:     |.   .|.:::...:|..|......|.....|..|.:.:|.::|.
Mosquito    47 LYGDYGAAGRTEHRI-----YTTQRLYREFKSKKWPIGGALMYLTPCVIPTDPHLIEFLLNEEFG 106

  Fly    99 NFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVI-TE 162
            .        |.:.......:|.   |:|.        :|.......:.....:.||:.|::: |.
Mosquito   107 K--------NKKSSIAGSSIFR---KRWS--------SFEDEHYNSLVNVATEESEKVVEMLCTS 152

  Fly   163 QVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFV 227
            :.|       :::|.:...:...:|..|.||..|    |..|....:.:|: .....|.:..:|.
Mosquito   153 KQP-------VDVKVIAELYAVRMIARCVFGKRC----TEESHTFPITEKL-ASQPGGIVWDVFS 205

  Fly   228 FSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENF--KRNDFMNLLIELKQKGRVTLDNGE 290
            .:||.......:|.: .|..|....|:::.::     :|  :|...:|.|..||:    |....:
Mosquito   206 TAFPSTTFTATLRKL-LDHFQKHPALLDELVS-----SFLTERTADVNFLQHLKR----TEQRAK 260

  Fly   291 VIEGMDIGELAAQVF-----VFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQ 350
            ..|.:..|:..|.:.     ||:||     |.|:..||:|:..|.|||..|...:|.
Mosquito   261 ANERIAFGDTRALMLELVQNVFFVA-----SGTIIACLFEMGHNGDIQKGLHETLQR-------- 312

  Fly   351 LTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDED 415
               .:..|:..|..|||||||.|..|..:....:.:..:|..| ||:.|.|:|::|..|...|.:
Mosquito   313 ---SNPFAVDTLENVISETLRKYPPVGEISFVTVANNRLPSGE-LVVPKNTRVVVPIYALQHDAE 373

  Fly   416 LYPNPETFDPER--FSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCD 478
            .||:||.|:|:|  ||    ::.:||.:.|.|..|.. ||.....:..|:.|:.|:.|..|.:..
Mosquito   374 HYPDPERFNPKRSIFS----SSEQSVLYRPLGVQPLP-IGSSLALLMVRVALSNILGRCTVRLTP 433

  Fly   479 TTEIPLKYSPMSIVLGTVGGIYLRVER 505
            .:...||.||...:....|.:.|.:.|
Mosquito   434 ESPATLKISPNQAMPYPTGRVELLISR 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	106/440 (24%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	106/442 (24%)