Protein Alignment Cyp6a2 and LOC4577153

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_061508324.1
• Gene: LOC4577153 / 4577153
• VectorBaseID: AGAMI1_013061
• Length: 501
• Species: Anopheles gambiae
• Alignment Length: 564
• Identity: 132/564 - (23%)
• Similarity: 223/564 - (39%)
• Gaps: 131/564 - (23%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGF-----------------RK 48
            ||....:|..|::|||.|   ::.|.:...:|.....|..||:|.|                 ..
Mosquito     1 MFYWAVVLGVIATLLAAL---DWKYKSYEHLPGPRRWPFIGNVVSFLGAGPVEIFDQLIAFASTY 62

  Fly    49 NRVMH-DFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDD 112
            .:|.. ||||||...|..   |......|..||                   |..:.|.::...:
Mosquito    63 GKVYKLDFFYDYTIIYSS---PEAAEAILTSPA-------------------FTAKSQDYDKVSE 105

  Fly   113 PLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKE 177
            .:...|.....:||...|:.:||.|.           .|:.|.||.|...|..|    ...:::.
Mosquito   106 WIGNGLLISRDQKWFTHRKVITPGFH-----------FKILENFVPVFNRQAEA----FCAKLET 155

  Fly   178 LMARFTTDVIGT------CAFGIECNTL---------RTPVSDFRTMGQKVFTDMRHGKLLTMFV 227
            |..| :.|.:..      ...||.|.|.         ::....:.|...:..:.:.:.::..:||
Mosquito   156 LTGR-SADAVNVFPELKLLTLGIICETAMGVGMDGEGQSTQQAYYTQIVEELSSILYWRMFNVFV 219

  Fly   228 ------------------------FSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKR 268
                                    |:...:..|.:|..:...|.:   |...:|...|:|.
Mosquito   220 NIDAVFRLTRTSRRFDELVKKSWQFTLGMIERRRKMNELEAPVEE---RNEEETFGKRKRA---- 277

  Fly   269 NDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQ 333
              .::.|:|.:..||...|.          |:..:|..|..||.:|::|.|::.||.:|::.:||
Mosquito   278 --LLDTLLEARIDGRPLTDE----------EIREEVDTFTFAGHDTTASAMTFILYNVAKHPEIQ 330

  Fly   334 DRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIE 398
            :|:..||...:.....:|:..::..:.|:..||.|:|||:..||.:.|.|..|..:....   |.
Mosquito   331 ERVYQEIVNEIGADFCELSLSALNNLHYMELVIKESLRLFPPVPVIARIATEDTELLAER---IT 392

  Fly   399 KGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARES-----VEWLPFGDGPRNCIGMRFGQ 458
            :||.|.|.....|..:|.:|:.|.|||:||.    .||::     ..::||..|.|||||.:|.|
Mosquito   393 RGTSVAIDIYTMHHSDDYFPDAERFDPDRFE----GARDAQTFNPYTYIPFSAGSRNCIGQKFAQ 453

  Fly   459 MQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLR 502
            .:.:..|.:::.||::.:.|.:.:|:..:  .|||....|:.||
Mosquito   454 YELKSTLVKLLQRFQIRLADASYVPILKA--EIVLKPAEGLPLR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	107/474 (23%)
LOC4577153	XP_061508324.1	None