Protein Alignment Cyp6a2 and cyp-25A3

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 155/487 - (31%)
• Similarity: 242/487 - (49%)
• Gaps: 36/487 - (7%)

  Fly     3 VLIYLLIAISSLLAYLY---HRNFNYWNRRGVPHDAPHPLYGNM--VGFRKNRVMHDFFYDYYNK 62
            :|..:|:::.|.:.|:.   ...|....:.|:....||.|.||:  :..||.::.:|..||:|||
 Worm     5 ILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYNK 69

  Fly    63 YRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLF-NLDGKKW 126
            ..|......|.||..:....|.:.:..|.:.||:||||:||.......|:.|.:.|. |.....|
 Worm    70 LHKQFGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTYESGW 134

  Fly   127 KDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCA 191
            |..|..:.|.|::||||.|..|:....:.|::::.|:   |.:|...:|.:.....|.||||.||
 Worm   135 KHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEK---ASSGQKWDIYDDFQGLTLDVIGKCA 196

  Fly   192 FGIECNTLRTPVSDFRTMGQKVFT--DMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLV 254
            |.|:.|..|.....|....:|..|  |:||.|:::. .|.||:|:...::.....|:.:..:.||
 Worm   197 FAIDSNCQRDRNDVFYVNARKFITNIDIRHSKIIST-SFLFPELSKLWKVLYRFTDLAKAEIPLV 260

  Fly   255 NDTIALRER----ENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETS 315
            .....:.||    |.....|.:.||:..:......:...||||         ..|.|.:||:||:
 Worm   261 EGLADVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIE---------NCFAFLLAGYETT 316

  Fly   316 SSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHL- 379
            |:.|:||.|.|::..::|.:|..||...  ::.|.|||:||..|.||:.|..||||.|..|.|.
 Worm   317 STAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDYVYKETLRCYPPVIHFS 379

  Fly   380 ERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFS--PEKVAARESVEWL 442
            .|:.|.|..:.|.   ...||..|:......||:.:.:.:||.|.||||.  .||   ..|::|:
 Worm   380 NRRCLKDITIRGQ---FYPKGAIVVCLPHTVHRNPENWDSPEEFHPERFENWEEK---SSSLKWI 438

  Fly   443 PFGDGPRNCIGMRFGQMQARIGLAQIISRFRV 474
            |||.|||.|:||||.:|:.:..:|:::..|.:
 Worm   439 PFGVGPRYCVGMRFAEMEFKTTIAKLLDTFEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	149/451 (33%)
cyp-25A3	NP_001040850.1	p450	37..496	CDD:278495	149/455 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16886
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.910