Protein Alignment Cyp6a2 and Cyp4a30b

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 548
• Identity: 135/548 - (24%)
• Similarity: 231/548 - (42%)
• Gaps: 107/548 - (19%)

  Fly     4 LIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHP--LYGNMVGFRKNRVMHDFFYDYYNKYRKS 66
            |:.||:.:.....|..||.:...:.:..| .||.|  |:||.:   |::.:.......      .
Mouse    24 LLGLLLLLLKSAQYYLHRQWLIKSLQQFP-PAPPPQWLFGNTL---KDQDLQQILLCV------E 78

  Fly    67 GFP--FVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDP------------LTQH 117
            .||  :|.:.:.:.....|.|....|.||               ||.||            :...
Mouse    79 KFPSTYVRWLWGNHARVVIYDPDYMKVIL---------------GRSDPKVVRSYSFFAPWIGYG 128

  Fly   118 LFNLDGKKWKDMRQRLTPTFTSGKMK----FMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKEL 178
            |..|:||||...|:.|||.|....:|    .|..:|..:.:::.:::.:..|       |||.:.
Mouse   129 LLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCP-------LEIYQD 186

  Fly   179 MARFTTDVIGTCAFGI-------ECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFP----- 231
            ::..|.:.:..|||..       :|...::.:.....:...::..:|:|......::|..
Mouse   187 ISLMTMETMMKCAFSYQGSVQLEDCRNSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRS 251

  Fly   232 -----KLASR-----LRMRMMPEDVHQFFMRLVNDTIALRERENF---KRNDFMNLLIELKQKGR 283
                 ::|.:     :|||.         .:|.|:.    |.|.|   ||.||:::|:..:.:..
Mouse   252 FYHACQIAHKHTERVIRMRK---------AQLQNEA----ELEKFRKKKRLDFLDILLFAQTEDG 303

  Fly   284 VTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE 348
            .:|.:.:|...||         .|...|..|::|.:|:..|.||.:.:.|.|.|.|::::|....
Mouse   304 KSLSDEDVRAEMD---------TFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGT 359

  Fly   349 GQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRD 413
             .:|...:..|.|....|.|.||||..:|...|:..:....|  :...:.||..|.:.....|.:
Mouse   360 -SVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFP--DGCSLPKGFLVTLSFYGLHHN 421

  Fly   414 EDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCD 478
            ..|.||.|.|||.||:|.  |.|::..:|||..|.|||||.:|...:.::.:|..:.||.: :.|
Mouse   422 PRLRPNAEVFDPSRFAPG--APRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFEL-LPD 483

  Fly   479 TTEIPLKYSPMSIVLGTVGGIYLRVERI 506
            .|.:|:..|  .|||.:..||||..:::
Mouse   484 PTRVPILVS--KIVLKSKNGIYLHTKKL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	117/473 (25%)
Cyp4a30b	XP_006503285.1	CYP4B-like	70..505	CDD:410771	120/492 (24%)