Protein Alignment Cyp6a2 and cyp4t8

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_954686.2
• Gene: cyp4t8 / 387527
• ZFINID: ZDB-GENE-031219-3
• Length: 509
• Species: Danio rerio
• Alignment Length: 541
• Identity: 131/541 - (24%)
• Similarity: 232/541 - (42%)
• Gaps: 85/541 - (15%)

  Fly     1 MFVLIYL--LIAISSLLAYLYHRNFNYWNRRGV------PHDAPHPLYGNMVGFRKNRVMHDF-- 55
            :|.||:|  |:.:..||..         .|:||      |....|.|:|::..||::.  ||.
Zfish    16 VFALIFLACLLTVVKLLIV---------RRKGVKTMERFPGPPAHWLFGHVKEFRQDG--HDLEK 69

  Fly    56 ---FYDYYNKYRKSGFPF-----VGFYFLHKPA---AFIVDTQLAKNILIKDFSNFADRGQFHNG 109
               :.:.|    :..||.     :....:|.|:   ..:..|:...:...|.|..:...|
Zfish    70 IVKWMELY----QFAFPLWFGPSLAVLNIHHPSYVKTILTTTEPKDDYAYKFFIPWLGDG----- 125

  Fly   110 RDDPLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPA-AQNGAVL 173
                    |....|:||...|:.|||.|....:|    ..:|:..:..||:.::... :::....
Zfish   126 --------LLVSTGQKWFRHRRLLTPGFHYDVLK----PYVKLISDSTKVMLDKWEVHSRSEESF 178

  Fly   174 EIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLA---- 234
            |:.:.::..|.|.|..|||  .||:.....|......|.|| |:.|...|...||.:...|
Zfish   179 ELFKHVSLMTLDSIMKCAF--SCNSNCQTDSGTNPYIQAVF-DLCHLVNLRFRVFPYHSKAIFHL 240

  Fly   235 --SRLRMRMMPEDVHQFFMRLV---NDTIALRERENFKRN----DFMNLLIELKQKGRVTLDNGE 290
              ...|.|......|.....::   .:.:.:.|.:...:|    ||:::|:..:.:.:
Zfish   241 SPHGYRFRKAASIAHNHTAEVIRKRKEVLKMEEEQGIVKNRRYLDFLDILLSARDEHQ------- 298

  Fly   291 VIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYES 355
              :|:...::.|:|..|...|.:|::|.:|:..|.||.|.:.|::.|.|||..| :.:..|.:|.
Zfish   299 --QGLSDEDIRAEVDTFMFEGHDTTASGISWIFYNLACNPEHQEKCRQEIQQAL-DGKATLEWED 360

  Fly   356 IKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNP 420
            :..:.|....|.|:|||:..||.:.||.......  .:...:.:|..:.:.....|.:..::.||
Zfish   361 LNKIPYTTMCIKESLRLHPPVPGISRKLTKPLTF--FDGRTVPEGCTIGVSIYGIHMNSTVWENP 423

  Fly   421 ETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLK 485
            ..|||.||.||.||.|....::||..|||||||..|...:.::.:|..:.|:.: :.|....| |
Zfish   424 YKFDPLRFLPENVANRSPHAFVPFSAGPRNCIGQNFAMNEMKVAVALTLKRYYL-IKDPDHTP-K 486

  Fly   486 YSPMSIVLGTVGGIYLRVERI 506
            ..| .:||.::.||:::::.:
Zfish   487 MIP-QVVLRSLNGIHIKIKPV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	120/492 (24%)
cyp4t8	NP_954686.2	p450	46..501	CDD:306555	121/495 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900