Protein Alignment Cyp6a2 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 219/507 - (43%)
• Similarity: 325/507 - (64%)
• Gaps: 8/507 - (1%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRK 65
            |.:|:.|::.:.:|:|:...:|:.||.|||:|||.|:...||.....:...:.......|.|:||
  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRK 65

  Fly    66 -SGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDM 129
             :..||.|||........|.|....|.:||:||..|.|||.:||.:|||||.:|..::|:|||::
  Fly    66 QTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWKNL 130

  Fly   130 RQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGI 194
            ||:||.||||.|||.||.||:.|.:|.::|:.|::  :.:...||:.::::|||:||||.||||:
  Fly   131 RQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKI--SSSSQTLEVTDIVSRFTSDVIGICAFGL 193

  Fly   195 ECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIA 259
            :||:||.|.::|..||.....:.|||.|:.:.:|..||||.:|..:.:...|.:|:|::|.|||.
  Fly   194 KCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTID 258

  Fly   260 LRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLY 324
            .|.:....|||||:.||::||:    .|.|:...|:...|:|||.|||::||||..|:||.:.||
  Fly   259 YRMKRKVTRNDFMDTLIDMKQQ----YDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLY 319

  Fly   325 ELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVV 389
            |||.|||:||:||.||.:|||...|:|.|:|::.:.|:.:||:|:||.:.:|.||.|.|...| .
  Fly   320 ELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPY-Q 383

  Fly   390 PGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGM 454
            ..:.|..||.||.|::.....|.|.:.||.||.|.||||..|:|..|.:..:||||.|||||||:
  Fly   384 HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGL 448

  Fly   455 RFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI 506
            |||:||..||||.:|..||..:...|.:|:||:..:::||:.|||:|.:.::
  Fly   449 RFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNITKV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	204/466 (44%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	207/469 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471824
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800