Protein Alignment Cyp6a2 and Cyp49a1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 120/540 - (22%)
• Similarity: 211/540 - (39%)
• Gaps: 135/540 - (25%)

  Fly    31 VPHDAPHPLYGN------MVGFRK----NRVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVD 85
            ||...|.||.||      ::|..|    ::||::...: |.|..|     ||....|....|:.|
  Fly   103 VPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVN-YGKMAK-----VGGLIGHPDLLFVFD 161

  Fly    86 TQLAKNI----------------------LIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKD 128
            ....:||                      |.:||  |.|            ...|..:.|.||:.
  Fly   162 GDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDF--FGD------------VAGLIGVHGPKWEA 212

  Fly   129 MRQRLTPTFTSGK-MKFMFPTVIKVSEEFVKVI------TEQVPAAQNGAVLEIKELMARFTTDV 186
            .||.:.......: .|...|.:..::.||:..|      .:::||       .....:.::..:.
  Fly   213 FRQEVQHILLQPQTAKKYIPPLNDIASEFMGRIELMRDEKDELPA-------NFLHELYKWALES 270

  Fly   187 IGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRM-RMMPEDVHQFF 250
            :|..:.......|....|:   ..|::.      :.:..|.::.|:|..|:.: |:.|...::.|
  Fly   271 VGRVSLDTRLGCLSPEGSE---EAQQII------EAINTFFWAVPELELRMPLWRIYPTKAYRSF 326

  Fly   251 MRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFV--------- 306
            ::.::...|                |.:|..|: |:|..:..|...:.:..|.:.:
  Fly   327 VKALDQFTA----------------ICMKNIGK-TMDKADADEARGLSKSEADISIVERIVRKTG 374

  Fly   307 -----------FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMT 360
                       .::.|.:|:|...|..:|:||:|.|.|.:|.:|:|.|...:|..:....::.|.
  Fly   375 NRKLAAILALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMP 439

  Fly   361 YLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDP 425
            ||...:.||||:..:|....|...:|.|:.|:.   :.|||.||.|......|...:|.|:.|.|
  Fly   440 YLRACVKETLRMRPVVIANGRSLQSDAVINGYH---VPKGTHVIFPHLVVSNDPAYFPEPKRFLP 501

  Fly   426 ERFSPEKV------AARESVE---WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV----- 476
            ||:..:..      .|.:.:.   .||||.|.|.|:|.||.:::....||:|..:::||.
  Fly   502 ERWLKQSTDAAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKVSYNSGEF 566

  Fly   477 ---CDTTEIPLKYSPMSIVL 493
               .::|.||  .||::..|
  Fly   567 VYRVNSTYIP--QSPLNFKL 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	106/492 (22%)
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	108/500 (22%)