Protein Alignment Cyp6a2 and Cyp6a13

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 225/505 - (44%)
• Similarity: 333/505 - (65%)
• Gaps: 18/505 - (3%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRK 65
            |..|:.|:..:..||......:::||:||||..:.|....|||.|..::....|.....|.|:|
  Fly     1 MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFR- 64

  Fly    66 SGFP-FVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDM 129
             |.. :.|::.....:.||:|.:|.::|:|:|||:|||||.|||.||||||.:|..|||.:|:.:
  Fly    65 -GVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFLDGPEWRWL 128

  Fly   130 RQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGI 194
            ||.||..|||||||||||.:::|.|:..:....||      ..:|.|:|.|||||||||:||||:
  Fly   129 RQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQV------GEIEAKDLCARFTTDVIGSCAFGL 187

  Fly   195 ECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIA 259
            |||:|:.|.|.||.||:.|..:..|..|:..|:|:.|:||.:||.|:...:|.:||:..|..|:.
  Fly   188 ECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTLD 252

  Fly   260 LRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLY 324
            .|.|||..|||.:.||:||.::|        |.:.:...::|||..||::|||:|||:|||:|||
  Fly   253 YRRRENIHRNDLIQLLMELGEEG--------VKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLY 309

  Fly   325 ELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVV 389
            |||.|.|:|:|||.|:..||:....:|||:|::.|.||:||::||||.|.::|||.|::..:|.:
  Fly   310 ELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQI 374

  Fly   390 PGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGM 454
            | :..|::|.|:::|||..:.|.|.:|||:||.|||.||.||::.||....:||||:|||||||.
  Fly   375 P-NSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGE 438

  Fly   455 RFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVE 504
            |||::|.::||..::..|:.|..:.|:||||:|..:.::.|..|::||:|
  Fly   439 RFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRME 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	211/466 (45%)
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	209/459 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471819
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.800