Protein Alignment Cyp6a2 and Cyp6a14

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 242/506 - (47%)
• Similarity: 336/506 - (66%)
• Gaps: 10/506 - (1%)

  Fly     8 LIAISSLLAYLYH-RNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSGFPFV 71
            |:.:...|||..| :.|:||.|:||||:.|.|:.|||.|..|.....|.....|.|::..| |..
  Fly     7 LVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKGQG-PIA 70

  Fly    72 GFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRLTPT 136
            |.|...|..|.|.|....|.::|||||.|.|||.|.|.||||||.|||.|:|::|:.||.:|||.
  Fly    71 GMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHKLTPV 135

  Fly   137 FTSGKMKFMFPTVIKVSEEFVKVITEQVPAA--QNGAVLEIKELMARFTTDVIGTCAFGIECNTL 199
            |||||:|.|...::.|.......:.:.|..|  :.|.| |||:|.|||||||||:||||:|||:|
  Fly   136 FTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNV-EIKDLCARFTTDVIGSCAFGLECNSL 199

  Fly   200 RTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERE 264
            :.|.::||..|:::||..||..|:..|:|:..:||.:||::::|:|:.||||..|.:|:..|.:.
  Fly   200 QDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYRLKN 264

  Fly   265 NFKRNDFMNLLIELKQKGRVTLDNGEVIE---GMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326
            ..|||||:..:|||:.:.:.....|:.|:   |:.:.::|||.|||:||||||||||||.|||||
  Fly   265 GIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYEL 329

  Fly   327 AQNQDIQDRLRNEIQTVLEEQE-GQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVP 390
            |...|||.|||.||::||...: |:|.|:.:..||||:||:|||||.:.|:|||.|:...||.:|
  Fly   330 ALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIP 394

  Fly   391 GHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMR 455
            ..: :|::||...:||....|.|.::||.||.|||.||.||:|..|..:.:||||||||||||:|
  Fly   395 NSD-IVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLR 458

  Fly   456 FGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI 506
            ||::||:|||..::.||:.||.:.|::||.:|..|.:|.|..||||:|||:
  Fly   459 FGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKVERV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	225/471 (48%)
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	228/476 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.970