Protein Alignment Cyp6a2 and CYP26C1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_899230.2
• Gene: CYP26C1 / 340665
• HGNCID: 20577
• Length: 522
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 82/359 - (22%)
• Similarity: 138/359 - (38%)
• Gaps: 85/359 - (23%)

  Fly   171 AVLE--IKELMARFTTDVIGTCAFGIECNTLRTPVS--------DFRTMGQKVFTDMRHGKL--- 222
            |.||  :..|......:|...||.|       .|||        .|| |..::...:|..:.
Human   152 AALERYVPRLQGALRHEVRSWCAAG-------GPVSVYDASKALTFR-MAARILLGLRLDEAQCA 208

  Fly   223 --------LTMFVFSFP------KLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMN 273
                    |...:||.|      .|...:|.|   :.:|:.....:::  .|.|.:..:..|.::
Human   209 TLARTFEQLVENLFSLPLDVPFSGLRKGIRAR---DQLHRHLEGAISE--KLHEDKAAEPGDALD 268

  Fly   274 LLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRN 338
            |:|...:      :.|......::.|.|.:  :.:.|.|.|:|::.|..|. |.|:.....::|.
Human   269 LIIHSAR------ELGHEPSMQELKESAVE--LLFAAFFTTASASTSLVLL-LLQHPAAIAKIRE 324

  Fly   339 EIQT------------VLEEQEG---------QLTYESIKAMTYLNQVISETLRLYTLVPHLERK 382
            |:..            .....||         .|:..::..:.|::.|:.|.|||...|....|.
Human   325 ELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRT 389

  Fly   383 ALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPN-PETFDPERFSPEKVAARES-------V 439
            ||..:.:.|::   |.||..|:......|....:|.: ||.||||||.    ||||.       .
Human   390 ALRTFELDGYQ---IPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFG----AAREDSRGASSRF 447

  Fly   440 EWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFR 473
            .::|||.|.|:|:|....|...::...:::...|
Human   448 HYIPFGGGARSCLGQELAQAVLQLLAVELVRTAR 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	82/359 (23%)
CYP26C1	NP_899230.2	CYP26C1	59..508	CDD:410729	82/359 (23%)