Protein Alignment Cyp6a2 and Cyp4f39

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_796281.1
• Gene: Cyp4f39 / 320997
• MGIID: 2445210
• Length: 532
• Species: Mus musculus
• Alignment Length: 548
• Identity: 129/548 - (23%)
• Similarity: 230/548 - (41%)
• Gaps: 90/548 - (16%)

  Fly     5 IYLLIAISSLLAYLYHR----------NFNYWNRRGVPHDAP---HPLYGNMVGFRKNR------ 50
            :|::.|:..|:.:.:.|          :|....|:......|   |.|.|:|..:..|.
Mouse    21 VYVVSALLLLVLFFFFRLLVRAFKLFSDFRITCRKLSCFPEPPGRHWLLGHMSMYLPNEKGLQNE 85

  Fly    51 -----VMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGR 110
                 .||.....:..       ||:       |...:|.....|.:|... :..|.:.:|....
Mouse    86 KKVLDTMHHIILAWVG-------PFL-------PLLVLVHPDYIKPVLGAS-AAIAPKDEFFYSF 135

  Fly   111 DDP-LTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITE--QVPAAQ---- 168
            ..| |...|....|.||...|:.|||.|.           ..:.:.::|:..:  .:..|:
Mouse   136 LKPWLGDGLLISKGNKWSRHRRLLTPAFH-----------FDILKPYMKIFNQCTNIMHAKWRRH 189

  Fly   169 --NGAV--LEIKELMARFTTDVIGTCAFGI--ECNTLRTPVSDF--RTMGQKVFTDMRHGKLLTM 225
              .|:|  .::.|.::..|.|.:..|.|..  :|   :..:||:  ..:........|..:|...
Mouse   190 LAEGSVTSFDMFEHISLMTLDSLQKCVFSYNSDC---QERMSDYISSIIELSALVVRRQYRLHHY 251

  Fly   226 FVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGE 290
            ..|.:...|...|.|...:.||.|      .|..::||....|.......::.|| |: |||..:
Mouse   252 LDFMYYLTADGRRFRQACDTVHNF------TTEVIQERRQALRQQGAEAWLKAKQ-GK-TLDFID 308

  Fly   291 VI------EGMDIG--ELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQ 347
            |:      ||.::.  ::.|:...|...|.:|:||.:|:.|:.||:..:.|::.|.|||.|::.:
Mouse   309 VLLLAKDEEGKELSDEDIRAEADTFMFEGHDTTSSGLSWALFNLAKYPEYQEKCREEIQEVMKGR 373

  Fly   348 E-GQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYH 411
            | .:|.::.:..:.:....|.|:||.:..|..:.|:...|..:|  :..||.||...::.....|
Mouse   374 ELEELDWDDLTQLPFTTMCIKESLRQFPPVTLISRRCTEDIKLP--DGRVIPKGIICLVSIYGTH 436

  Fly   412 RDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
            .:..::|:.:.::|.||.|:....|..:.::||..|||||||..|...:.|:.:|..:.|||:||
Mouse   437 HNPIVWPDSKVYNPYRFDPDTPQQRSPLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRLSV 501

  Fly   477 CDTTEIPLKYSPMSIVLGTVGGIYLRVE 504
            ..|.::..|   ..::|.|..|::|.||
Mouse   502 DRTHKVRRK---PELILRTENGLWLNVE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	120/503 (24%)
Cyp4f39	NP_796281.1	p450	60..515	CDD:365848	117/496 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900