Protein Alignment Cyp6a2 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 136/562 - (24%)
• Similarity: 238/562 - (42%)
• Gaps: 107/562 - (19%)

  Fly     1 MFVLIYLLIAISSLLA--YLYHRNF-------NYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFF 56
            ||::|..::| |:|..  .|||..|       :|     :|.....||.|:         .|.|.
  Fly     1 MFLVIGAILA-SALFVGLLLYHLKFKRLIDLISY-----MPGPPVLPLVGH---------GHHFI 50

  Fly    57 YDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILI---KDFS------NFADRGQFHNGRDD 112
            ....::..|..|.|:..|...:.....:..:|  |:|:   ||..      .|.|:...:...:.
  Fly    51 GKPPHEMVKKIFEFMETYSKDQVLKVWLGPEL--NVLMGNPKDVEVVLGTLRFNDKAGEYKALEP 113

  Fly   113 PLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVI----------TEQVPAA 167
            .|.:.|....|:||...|:.:||.|.           .|:.::||:|.          .||....
  Fly   114 WLKEGLLVSRGRKWHKRRKIITPAFH-----------FKILDQFVEVFEKGSRDLLRNMEQDRLK 167

  Fly   168 QNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLT-MFVFSFP 231
            ...:...:.:.:...|.|.|...|.|:..|......|:: ....|..:.:.|.::.. ::.|...
  Fly   168 HGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEY-VQAVKTISMVLHKRMFNILYRFDLT 231

  Fly   232 KLASRL-RMRMMPEDV-HQFFMRLVNDTIALRERENFKR--------ND-----------FMNLL 275
            .:.:.| |......:| |||     .:.|.::.||...|        ||           |:::|
  Fly   232 YMLTPLARAEKKALNVLHQF-----TEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDIL 291

  Fly   276 IELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEI 340
            ::      .|:|. ..:..:||.|   :|..|...|.:|:||.:.:..|.:|.:.:.|.:...||
  Fly   292 LQ------STVDE-RPLSNLDIRE---EVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEI 346

  Fly   341 QTVL-EEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVI 404
            ::|: .::...::||.:..:.|::..:.||||:|..||.|.||.|.|..:.|.   :|..||.:.
  Fly   347 RSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGK---LIPAGTNIG 408

  Fly   405 IPACAYHRDEDLYPNPETFDPERFSPEKVAARESVE---WLPFGDGPRNCIGMRFGQMQARIGLA 466
            |......|.|:|:..|..|.||||  :.|...|.:.   ::||..|||||||.:|..::.:..:|
  Fly   409 ISPLYLGRREELFSEPNIFKPERF--DVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471

  Fly   467 QIISRFRVS-VCDTTEIPLKYSPMSIVLGTVGGIYLRV-ERI 506
            .::..:.|. |.|::|.|:..:  .::|.|...:..:| ||:
  Fly   472 NVLRHYEVDFVGDSSEPPVLIA--ELILRTKEPLMFKVRERV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	114/476 (24%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	112/466 (24%)