Protein Alignment Cyp6a2 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 127/527 - (24%)
• Similarity: 226/527 - (42%)
• Gaps: 73/527 - (13%)

  Fly    11 ISSLLAYLYHRNFNYWNRRGVPHDAPHP--LYGNMVGFRKNRVMHDFFYDYYNKYRKSGFPFVGF 73
            ::.:||::|....|....|..| ..|.|  .:|::...:.|.....|.......:|.....:||.
  Rat    32 LARILAWIYTFYDNCCRLRCFP-QPPKPSWFWGHLTLMKNNEEGMQFIAHLGRNFRDIHLSWVGP 95

  Fly    74 YF----LHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDP-LTQHLFNLDGKKWKDMRQRL 133
            .:    |..|.......|.:..:..|:.:.:        |...| |...|....|:||...|:.|
  Rat    96 VYPILRLVHPNVIAPLLQASAAVAPKEMTLY--------GFLKPWLGDGLLMSAGEKWNHHRRLL 152

  Fly   134 TPTFTSGKMKFMFPTVIKVSEEFVKVITEQVP---------AAQNGAVLEIKELMARFTTDVIGT 189
            ||.|.           ..:.:.:||:..:.|.         .|:..|.|::.|.::..|.|.:..
  Rat   153 TPAFH-----------FDILKSYVKIFNKSVNTMHAKWQRLTAKGSARLDMFEHISLMTLDSLQK 206

  Fly   190 CAFGIECNTLRTP---VSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFM 251
            |.|..:.|...:.   ::....:...:....|...|...|::..  .|...|.|...:.||.|..
  Rat   207 CIFSFDSNCQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYL--TADGRRFRKACDVVHNFTD 269

  Fly   252 RLVNDTIA----------LRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFV 306
            .::.:..:          |:.|...|..||:::|:..|.      ::|:.:..:||   .|:...
  Rat   270 AVIRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKD------EHGKGLSDVDI---RAEADT 325

  Fly   307 FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE-GQLTYESIKAMTYLNQVISETL 370
            |...|.:|::|.:|:.||.||::.:.|:|.|.|::.:|.::| .::.::.:..:.:|...|.|:|
  Rat   326 FMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESL 390

  Fly   371 RLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAA 435
            ||:..|..:.|....|.|:|  :..||.||...:|.....|.:..::|:||.::|.||.||....
  Rat   391 RLHPPVLLISRCCSQDIVLP--DGRVIPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDPENPQK 453

  Fly   436 RESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM---SIVLGTVG 497
            |..:.::||..|||||||..|...:.::.||..:.||.|       :|....|.   .::|...|
  Rat   454 RSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCV-------LPDDKEPRRKPELILRAEG 511

  Fly   498 GIYLRVE 504
            |::||||
  Rat   512 GLWLRVE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	111/461 (24%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	113/479 (24%)