Protein Alignment Cyp6a2 and Cyp4a8

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_038965258.1
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 510
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 136/533 - (25%)
• Similarity: 230/533 - (43%)
• Gaps: 76/533 - (14%)

  Fly     3 VLIYLLIAISSLLAYLYHRNFNYWNRRGV---PHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYR 64
            ||..||:...:...||:.|    |..|..   |....|..:|:.:.|..::...|..      .|
  Rat    24 VLTVLLLLFKTAQFYLHRR----WLLRATQQFPSPPSHWFFGHKLSFLVDQEFQDIL------TR 78

  Fly    65 KSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQH------------ 117
            ...||.....:|           ...|:.|:.:.  .|..:...||.||.:.|
  Rat    79 VKNFPSACPQWL-----------WGSNVRIQVYD--PDYMKLILGRSDPKSHHSYRFLAPWIGYG 130

  Fly   118 LFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVIT---EQVPAAQNGAVLEIKELM 179
            |..|:|:.|...|:.|||.|....:|    ..:.:..:.|:::.   ||:  ....:.|||.:.:
  Rat   131 LLLLNGQTWFQHRRMLTPAFHYDTLK----PYVGIMADSVRIMLDKWEQI--VGQDSTLEIFQHI 189

  Fly   180 ARFTTDVIGTCAFGIECNT-----LRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLR- 238
            ...|.|.|..|||..|.:.     .::.:.....:....|..:|:.......::|......:.|
  Rat   190 TLMTLDTIMKCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARS 254

  Fly   239 -MRMMPEDVHQFF---MRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGE 299
             .::..|...|..   ...:.|...|::.:..:|.||:::|:..:      ::||..:...|
  Rat   255 AWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFAR------IENGSSLSDKD--- 310

  Fly   300 LAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQ 364
            |.|:|..|...|.:|::|.:|:..|.||.|.:.|...|.|||::|.: ...:|::.:..|.|...
  Rat   311 LRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGD-GASITWDDLDKMPYTTM 374

  Fly   365 VISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFS 429
            .|.|.||:|..|..:.|........|....|  .||..|::.....|.:..::||||.|||.||:
  Rat   375 CIKEALRIYPPVTAVSRMLSTPVTFPDGRSL--PKGITVMLSFYGLHHNPTVWPNPEVFDPYRFA 437

  Fly   430 PEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM-SIVL 493
            ||  ::|.|..:|||..|.|||||.:|...:.::.:|..:.||.: :.|.|.||:   |: .:||
  Rat   438 PE--SSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRIPI---PIPRLVL 496

  Fly   494 GTVGGIYLRVERI 506
            .:..|||||::::
  Rat   497 KSKNGIYLRLKKL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	124/491 (25%)
Cyp4a8	XP_038965258.1	CYP4B-like	72..505	CDD:410771	121/475 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900