Protein Alignment Cyp6a2 and erg5

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_593788.2
• Gene: erg5 / 2542469
• PomBaseID: SPAC19A8.04
• Length: 543
• Species: Schizosaccharomyces pombe
• Alignment Length: 546
• Identity: 126/546 - (23%)
• Similarity: 221/546 - (40%)
• Gaps: 120/546 - (21%)

  Fly     2 FVLIYLLIAISSLLAYLYHRNFNYWNRRG-VPHDAPH---PLYGNMVGFRKNRVMHDFFYDYYNK 62
            :.:.:.|:|:  .:||   ...:|..::| :|  .|.   |..|:.:...|..      ::.||.
pombe    29 WTICFALLAV--CIAY---DQISYQMQKGHIP--GPRFKIPFMGSFLDSMKPT------FEKYNA 80

  Fly    63 YRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSN--------FADRGQFHNGRDDPLTQH-- 117
            ..::| |.......||......:..||:.||     |        ..|.|:       .:.:|
pombe    81 KWQTG-PLSCVSVFHKFVVIASERDLARKIL-----NSPSYVQPCVVDAGK-------KILKHTN 132

  Fly   118 -LFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMAR 181
             :| |||:...:.|:.|...||:..:....|....|..::.|   |.:..:::    :..:.|..
pombe   133 WVF-LDGRDHIEYRKGLNGLFTTRALASYLPAQEAVYNKYFK---EFLAHSKD----DYAQYMIP 189

  Fly   182 FTTDVIGT-----CAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMF--VFSFPKLASRLRM 239
            |....:.|     |.:.|..:.::....::    .|:...|.    |..|  |..|.|:...::.
pombe   190 FRDINVATSCRTFCGYYISDDAIKHIADEY----WKITAAME----LVNFPIVLPFTKVWYGIQS 246

  Fly   240 RMMPEDVHQFFMRLVNDTIALRERENFK--------RNDFMNLLIELKQKGRVTLDNGE----VI 292
            |.:   |.::||:     .|...|:|.:        ..::::.:||.::......:..|    :|
pombe   247 RKV---VMRYFMK-----AAAESRKNMEAGNAPACMMEEWIHEMIETRKYKSENKEGAEKPSVLI 303

  Fly   293 EGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQ----LTY 353
            ......|::.....|..|..:.:||.|::....||.:.|:..::|.|   .|..::|.    |:.
pombe   304 REFSDEEISLTFLSFLFASQDATSSAMTWLFQLLADHPDVLQKVREE---QLRIRKGDIDVPLSL 365

  Fly   354 ESIKAMTYLNQVISETLRL---YTLVPHLERKAL---NDYVVPGHEKLVIEKGTQVIIPACAYHR 412
            :.::.|||...|:.|.|||   ..:||:..:||.   .||.||        |...||........
pombe   366 DLMEKMTYTRAVVKECLRLRPPVLMVPYRVKKAFPITPDYTVP--------KDAMVIPTLYGALH 422

  Fly   413 DEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRF--GQMQARIGLAQII---SRF 472
            |..:||.||||:|:|::|..:|.:....|:.||:||..|:|.|:  ..:.|.||.|.|:   ...
pombe   423 DSKVYPEPETFNPDRWAPNGLAEQSPKNWMVFGNGPHVCLGQRYAVNHLIACIGKASIMLDWKHK 487

  Fly   473 RVSVCDT-----TEIP-----LKYSP 488
            |....||     |..|     ||:||
pombe   488 RTPDSDTQMIFATTFPQDMCYLKFSP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	112/475 (24%)
erg5	NP_593788.2	CYP61_CYP710	85..507	CDD:410703	109/469 (23%)