Protein Alignment Cyp6a2 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 537
• Identity: 148/537 - (27%)
• Similarity: 261/537 - (48%)
• Gaps: 58/537 - (10%)

  Fly     3 VLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSG 67
            |.:.||:|:.:||.:.....|:...:.|:.|..|.|..||::.||:.      |::...:.|:..
Mouse    16 VTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQG------FWESQLELRERY 74

  Fly    68 FPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPL-TQHLFNLDGKKWKDMRQ 131
            .|..|:|...:....|.:..:.|.:|:::||||::|  ..:|.:..: ...:..|..::|:::|.
Mouse    75 GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNR--MASGLEPKMVADSVLLLRDRRWEEVRG 137

  Fly   132 RLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIEC 196
            .|..:|:..|:..|.|.:.:..|..|..:...  ||...| ..|:.....:|.||:.:.|||.:.
Mouse   138 ALMSSFSPEKLDEMTPLISQACELLVAHLKRY--AASRDA-FNIQRCYCCYTIDVVASVAFGTQV 199

  Fly   197 NTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMP----EDVHQFFMRLVNDT 257
            ::..:|...|....::..|......||.: :.|||.:...| .|::|    ::::.||..|:.:.
Mouse   200 DSQNSPEDPFVQHCRRASTFCIPRPLLVL-ILSFPSIMVPL-ARILPNKNRDELNGFFNTLIRNV 262

  Fly   258 IALRERE--NFKRNDFMNLLIELKQKGRVTLDNGEVIEGMD------------------------ 296
            ||||:::  ..:|.||:.::::.:..     .|...:||.|
Mouse   263 IALRDQQAAEERRRDFLQMVLDAQHS-----MNSVGVEGFDMVPESLSSSECTKEPPQRCHPTST 322

  Fly   297 -----IGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESI 356
                 :.|:..|.|:|.:||.|..::|:|:..|.||.:.|.|:||..|:...:.:......:...
Mouse   323 SKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQ 387

  Fly   357 KAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPE 421
            :.:.||:.|||||||:|.......|:|..|..|.|..   |..||.:.|...|.|.|.:.:||||
Mouse   388 EGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR---IPAGTVLEIAVGALHHDPEHWPNPE 449

  Fly   422 TFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKY 486
            |||||||:.|....|....:||||.|||:|:|:|.|.:..::.:.|::.:||......|::||:.
Mouse   450 TFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPLQL 514

  Fly   487 SPMSIVLGTVGGIYLRV 503
            ...| .||...|:|:::
Mouse   515 ESKS-ALGPKNGVYIKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	130/466 (28%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	130/468 (28%)