Protein Alignment Cyp6a2 and cyp-13A2

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 134/524 - (25%)
• Similarity: 227/524 - (43%)
• Gaps: 74/524 - (14%)

  Fly     2 FVLIYLLIAISSLLAYLYHRNFNYWNRRGV--PHDAPHPLYGNMVGFRKNRVMHDF-----FYDY 59
            |||.........:|.| |...:.||.|:||  |...|      .||.....:.|:.     ..::
 Worm     5 FVLAVTFSIFLGILTY-YLWIWTYWMRKGVKGPRGRP------FVGVLDVLLEHETPGLIKLGEW 62

  Fly    60 YNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADR--GQFHNGRDDPLTQHLFNLD 122
            ..||.|    ..|:....:....:.|..:...|.:|.|.||..|  .......:.....||....
 Worm    63 TKKYGK----VYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQ 123

  Fly   123 GKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVI 187
            |.:||.:|...:.:|::..:|.|..||...:.|.::.|.:|   ...|..:::......:|.|||
 Worm   124 GYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQ---TAGGEQIDMLRFYQEYTMDVI 185

  Fly   188 GTCAFG-IECNTLRTPVSDFRTMGQKVFTDMRH------------GKLLTMFVFSFPKLASRLRM 239
            |..|.| .:....:.|:.:   :.:::|...|.            |:.:....|.||::.: .::
 Worm   186 GRFAMGQTDSMMFKNPIVN---VVREIFCGSRKNLMLICQVFPPIGQFIRDLTFKFPRIPA-FKL 246

  Fly   240 RMMPEDVHQFFMRLVNDTIALRER----ENFKRNDFMNLLIELKQ---------KGRVTLDNGEV 291
            ..:.:||       |...||.|||    |:.:..||::|.::.:.         :...:..|.::
 Worm   247 YSIMQDV-------VAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKI 304

  Fly   292 IEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESI 356
            .:.:...|:..|.|:|.:.||:|::.::||..|.||.|..||:::..||  ..|....::.:|.:
 Worm   305 TKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEI--AREFGTSEVEFEKL 367

  Fly   357 KAMTYLNQVISETLRLYTLVP-HLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNP 420
            ..:.|::.||.|.||||.|.. ...||.:....|.|   :.||.|..|.:...:.|.|.:|:..
 Worm   368 GRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNG---VKIEAGVYVQMDTWSLHYDPELWGE- 428

  Fly   421 ETFDPERFSPEKVAARESVE----WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTE 481
               |.:.|.||:.:..|.:|    :||||.|||.|||||...|:.:|.|..::..:.....:.|.
 Worm   429 ---DVKEFKPERWSTDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNKTR 490

  Fly   482 IPLK 485
            ||||
 Worm   491 IPLK 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	122/488 (25%)
cyp-13A2	NP_496109.1	p450	35..511	CDD:278495	123/493 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4378
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.680