Protein Alignment Cyp6a2 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 141/528 - (26%)
• Similarity: 243/528 - (46%)
• Gaps: 85/528 - (16%)

  Fly     4 LIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYY--NKYRKS 66
            :|:.||.||.:..|.:|  :.:|.|||:|.....|::|     :...::.|.|...|  .|:.|.
 Worm     1 MIFELILISIVTYYFWH--WTFWKRRGLPGPWGVPIFG-----KAGAMLEDSFPPGYTLQKWTKE 58

  Fly    67 GFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNG-RDDPLTQ---HLFNLDGKKWK 127
            .....||....:....|.|..|.:.||:|.:.||  .|:.||. :.||...   |:....|.:||
 Worm    59 YGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNF--YGRKHNPVQGDPDKDKDIHIVGAQGFRWK 121

  Fly   128 DMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAF 192
            .:|....|.|::|.:|.:..|:...::|.:|.:.|:   ::||..:.:......:|.|||...|.
 Worm   122 RLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREE---SENGKAVNMHLFYQEYTFDVISRVAM 183

  Fly   193 G-----IECNTLRTPVSDFRTMGQKVFTDMRHGK-LLTMFVFSFPKLASRLRMRMMPEDVHQF-- 249
            |     :..|.|...|..|          ..|.: .:.||...||...|.|:...:  .|.:|
 Worm   184 GQPDSQMFKNPLLKDVKGF----------FEHNRWQIWMFSGGFPFAVSFLKWLFI--KVGKFGA 236

  Fly   250 -----FMRLVNDTIALR--ERENFKRND------------FMNLLIELKQKGRVTLDNGEVIEG- 294
                 ..:.|.|.:..|  :||..|::.            |:|...|::..|.   .|.|..:.
 Worm   237 GPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGE---SNDEFHKSS 298

  Fly   295 ------MDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTY 353
                  :...|:.:|.|||.||||:|::.::||..|.||.|..||.:|::|:..  |....::|:
 Worm   299 SYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK--ECPNDEITF 361

  Fly   354 ESIKAMTYLNQVISETLRLYTLVPHL-ERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY 417
            :.:..:.|::.||.|:|||:...... .|:.:.:.|: |.:  ::|.|..|:|.....|.|::::
 Worm   362 DQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVI-GEQ--IVEAGVDVMIDTWTLHHDKNVW 423

  Fly   418 PNP-ETFDPERF----SPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVC 477
            .|. |.|.|||:    :|::.       :|.||.|||.|:||||..::.:..|:.|:.::.....
 Worm   424 GNDVEEFKPERWDSPLTPQQA-------YLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETN 481

  Fly   478 DTTEIPLK 485
            ..|::|:|
 Worm   482 AKTQLPIK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	122/461 (26%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	122/464 (26%)