Protein Alignment Cyp6a2 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 136/539 - (25%)
• Similarity: 245/539 - (45%)
• Gaps: 75/539 - (13%)

  Fly     1 MFVLI-YLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHD---FFYDYYN 61
            :|||: .:|:.:.:...:::    :|:.|:|:......|..|.::    ..:.|:   |.  .|.
 Worm     2 IFVLLSAVLLGVFTYSVWIW----SYFIRKGIKGPRGFPGIGMLI----QTIDHENPPFL--KYR 56

  Fly    62 KYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQ---HLFNLDG 123
            .:.|...|..||....:....|.:.::...|..|.|.||..| :......||...   ::|:..|
 Worm    57 DWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGR-KLRPIIGDPEKDKRVNIFSTQG 120

  Fly   124 KKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIG 188
            |:||.:|...:|:|::..::.:..:|.:...|.:..|.::|...::   :::..:...:|..||.
 Worm   121 KRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNED---IDMLIVYQEYTLGVIS 182

  Fly   189 TCAFG-IECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLAS--RLRMRMMPED----- 245
            ..|.| .|.|..:.|:   ....|.:|....|..|:|..   ||.||.  |...:|:|..
 Worm   183 RIALGQSESNMFKNPL---LPKVQAIFNGSWHVFLITGI---FPPLAGVFRKMSKMLPASFIPAF 241

  Fly   246 -VHQFFMRLVNDTIALRERENFK------RNDFMNLLIELKQKGRVTLDNGEVIEG--------- 294
             :.......|...|..|.::..|      ..||::|.::.:... |.:.:||..|.
 Worm   242 KIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDARVPD-VKILSGEANEDFAKSSVVKI 305

  Fly   295 ---MDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESI 356
               :...|:.||.|||..|||:|::.::||..|.||.:.:||.:|:.|:..  |..:.::.::.:
 Worm   306 NKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDR--ECPDPEIFFDHL 368

  Fly   357 KAMTYLNQVISETLRLYTL-VPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PN 419
            ..:.||..|:.||||||.| .....||.:.:..:.|   :..::|..:.:.....|.:..:: .:
 Worm   369 SKLKYLECVMKETLRLYPLGTTANTRKCMRETTING---VNFDEGMNIQVDTWTLHHNPRIWGED 430

  Fly   420 PETFDPERFSPEKVAARESVE----WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTT 480
            .|.|.|||:   :..|.|.:|    ::|||.|||.|||||..||:.:|.||||:..:.......|
 Worm   431 VEDFKPERW---ENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNT 492

  Fly   481 EIPLK------YSPMSIVL 493
            :||:|      .||.|:::
 Worm   493 QIPVKLVGKLTLSPESVIV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	123/467 (26%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	123/468 (26%)