Protein Alignment Cyp6a2 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 142/552 - (25%)
• Similarity: 242/552 - (43%)
• Gaps: 109/552 - (19%)

  Fly     7 LLIAISSLLAYL--YHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYN-------K 62
            :|||.:|.:..|  |...:::|.|:||......|.:|         |:|: |.||.|       :
 Worm     5 ILIAGASFIGLLTYYIWIWSFWIRKGVKGPRGFPFFG---------VIHE-FQDYENPGLLKLGE 59

  Fly    63 YRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPL--------TQHLF 119
            :.|...|..|.....:....:.:.:....:.:|.|.||..|      :.:|:        ..||.
 Worm    60 WTKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGR------KTNPIQGDPNKNKRAHLV 118

  Fly   120 NLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTT 184
            :..|.:||.:|...:|||::..::.:..|   |.|..|:::.....|:..|..:::.:....||.
 Worm   119 SAQGHRWKRLRTLSSPTFSNKNLRKIMST---VEETVVELMRHLDDASAKGKAVDLLDYYQEFTL 180

  Fly   185 DVIGTCAFG-IECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFS-FPKLASRLRMRMMPEDVH 247
            |:||..|.| .|....|.|      |..||....:.|:.|...|.. ||...:..|
 Worm   181 DIIGRIAMGQTESLMFRNP------MLPKVKGIFKDGRKLPFLVSGIFPIAGTMFR--------- 230

  Fly   248 QFFMRLVN-----DTIALRERENFKR------------------NDFMNLLIELKQK-------- 281
            :||||..:     |.::..|:...||                  .||::|.::.:..
 Worm   231 EFFMRFPSIQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEES 295

  Fly   282 --GRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVL 344
              |....:..:|.:.:...|:..|:|||.:||::|::.::||..|.||::.:||.:|:.|:..
 Worm   296 ALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR-- 358

  Fly   345 EEQEGQLTYESIKAMTYLNQVISETLRLYTL--VPHLERKALNDYVVPGHEKLVIEKGTQVIIPA 407
            |....::|::.|..:.|:..|:.|.||:|.|  :.| .||.:.:..|.|   :.|||||.|.:..
 Worm   359 ECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVH-NRKCMKETNVLG---VQIEKGTNVQVDT 419

  Fly   408 CAYHRDEDLYPNPETFDPERFSPEKVAARESV-----EWLPFGDGPRNCIGMRFGQMQARIGLAQ 467
            ...|.|..::..    |...|.||:..:.:.:     .:||||.|||.|||||...|:.::.|..
 Worm   420 WTLHYDPKVWGE----DANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTH 480

  Fly   468 IISRFRVSVCDTTEIPLKY------SPMSIVL 493
            |:.::.......||||||.      :|.|::|
 Worm   481 ILKKYTFETSTQTEIPLKLVGSATTAPRSVML 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	123/481 (26%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	122/481 (25%)