Protein Alignment Cyp6a2 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 144/489 - (29%)
• Similarity: 230/489 - (47%)
• Gaps: 36/489 - (7%)

  Fly     1 MFVLIYLLIAISSLLAYLY---HRNFNYWNRRGVPHDAPHPLYGNM--VGFRKNRVMHDFFYDYY 60
            :.:|..|:|:|.:...|:.   ...|....:.|:....||...||:  ...||.::.:|....::
 Worm     3 LLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWF 67

  Fly    61 NKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQH-LFNLDGK 124
            |:..:......|.|:..:....|.:.:..|.:.||:||||:||........:.||.. |.|....
 Worm    68 NELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYSS 132

  Fly   125 KWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGT 189
            .||..|..:.|.|::||||.|..|:....:.|:.::.|:   |.:|...:|.:.....|.||||.
 Worm   133 GWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREK---ASSGQKWDIYDDFQGLTLDVIGK 194

  Fly   190 CAFGIECNTLRTPVSDFRTMGQKVFT--DMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMR 252
            |||.|:.|..|.....|....:|..:  |:||.|::...|. .|:|::..:.......:....:.
 Worm   195 CAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVL-LPELSTFWKALYKYTPLADAEIP 258

  Fly   253 LVNDTIALRER----ENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFE 313
            ||.....:.||    |.....|.:.||:..:......:...||||         ..|.|.:||:|
 Worm   259 LVEGLSNVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIE---------NCFAFLLAGYE 314

  Fly   314 TSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPH 378
            |:|:.|:||.|.|::..::|.:|..||...  ::.|.|||:||..|.||:.|..||||.|..|.|
 Worm   315 TTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDCVYKETLRFYPPVIH 377

  Fly   379 -LERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFS--PEKVAARESVE 440
             :.|....|..:.|.   ...||..|:......||:.:.:.:||.|.||||.  .||   ..|::
 Worm   378 FIRRLCREDITIRGQ---FYPKGAIVVCLPHTVHRNPENWDSPEEFHPERFENWEEK---SSSLK 436

  Fly   441 WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRV 474
            |:|||.|||.|:||||.:|:.:..:.:::..|.:
 Worm   437 WIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	129/416 (31%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	129/419 (31%)