Protein Alignment Cyp6a2 and cyp-25A2

DIOPT Version :9

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 148/489 - (30%)
• Similarity: 230/489 - (47%)
• Gaps: 36/489 - (7%)

  Fly     1 MFVLIYLLIAISSLLAYLY---HRNFNYWNRRGVPHDAPHPLYGNM--VGFRKNRVMHDFFYDYY 60
            :.:|..:||.:.|.:.|:.   ...|....:.|:....||...||:  :..||.::.:|....::
 Worm     3 LLILTSILILLVSFIIYILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDRKEKLGYDDSNKWF 67

  Fly    61 NKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLF-NLDGK 124
            |:..|......|.||..:....:.:.:..|.:.||:||||:||........:.|.|.|. |....
 Worm    68 NELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTYAT 132

  Fly   125 KWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGT 189
            .||..|..:.|.|::||||.|..|:....:.|:.::.|:   |.:|...:|.|.....|.||||.
 Worm   133 GWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREK---ASSGQKWDIYEDFQGLTLDVIGK 194

  Fly   190 CAFGIECNTLRTPVSDFRTMGQKVFT--DMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMR 252
            |||.|:.|..|.....|....:|...  |:||.|::.. .|..|:||...|.......:....:.
 Worm   195 CAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAA-SFILPELAPLWRALYKYTPLADAEIP 258

  Fly   253 LVNDTIALRER----ENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFE 313
            ||.....:.||    |.....|.:.||:..:......:...||||         ..|.|.:||:|
 Worm   259 LVEGLSNVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIE---------NCFAFLLAGYE 314

  Fly   314 TSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPH 378
            |:|:.|:||.|.|::..::|.:|..||...  ::.|.|||:||..|.||:.|..||||.|..|.|
 Worm   315 TTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDYVYKETLRCYPPVIH 377

  Fly   379 -LERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFS--PEKVAARESVE 440
             :.|:.|.|..:.|.   ...||:.|.......|.:.:.:.:||.|.||||.  .||   ..|::
 Worm   378 FINRRCLADITIRGQ---FYPKGSVVTCLPHTVHLNPENWDSPEEFHPERFENWEEK---SSSLK 436

  Fly   441 WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRV 474
            |:|||.|||.|:||||.:|:.:..:.:::..|.:
 Worm   437 WIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	141/451 (31%)
cyp-25A2	NP_497776.2	p450	38..498	CDD:278495	141/454 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	LDO	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880