Protein Alignment Cyp6a2 and Cyp4f13

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_570952.1
• Gene: Cyp4f13 / 170716
• MGIID: 2158641
• Length: 523
• Species: Mus musculus
• Alignment Length: 534
• Identity: 125/534 - (23%)
• Similarity: 233/534 - (43%)
• Gaps: 88/534 - (16%)

  Fly    11 ISSLLAYLYHRNFNYWNRRGVPHDAPHP--LYGNMVGFRKN--------RVMHDFFYDYYNKYRK 65
            ::.:||::|....|....|..| ..|.|  .:|::...:.|        .:.|| |:|.:..:..
Mouse    31 LARILAWIYAFYDNCSRLRCFP-QPPKPSWFWGHLALMKNNEESMQFITHLGHD-FHDVHLSWVG 93

  Fly    66 SGFPFVGFYF------LHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGK 124
            ..:|.:....      |.:.:|.:...::.....:|.:                |...|....|.
Mouse    94 PVYPILRLVHPNFIAPLLQASAAVAPKEMTLYGFLKPW----------------LGDGLLMSAGD 142

  Fly   125 KWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITE--QVPAAQNGAVLEIKELMARFTTDVI 187
            ||...|:.|||.|....:|    :.:|:..:.|.::..  |..|::..:.|::.|.::..|.|.:
Mouse   143 KWSHHRRLLTPAFHFDILK----SYVKIFNKSVNIMHAKWQCLASKGTSRLDMFEHISLMTLDSL 203

  Fly   188 GTCAFGIECNTLRT------PVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDV 246
            ..|.|.::.|...:      .:.:..::..|     ||.:........:...|...|.|...:.|
Mouse   204 QKCIFSVDSNCQESDSKYIAAILELSSLVVK-----RHRQPFLYLDLLYYLTADGRRFRKACDLV 263

  Fly   247 HQFFMRLVNDTIALRERE---NFKRNDFMNLLIELKQKGRV-TLDNGEVI--------EGMDIGE 299
            |.|     .|.: ::||.   |.:..:|      ||.|.:. |||..:|:        :|:...:
Mouse   264 HNF-----TDAV-IKERRSTLNTQGVEF------LKAKAKTKTLDFIDVLLMAEDEHGKGLSNED 316

  Fly   300 LAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEG-QLTYESIKAMTYLN 363
            :.|:...|...|.:|::|.:|:.||.||::.:.|:|.|.|:|.:|.:::. ::.::.:..:.:|.
Mouse   317 IRAEADTFMFGGHDTTTSALSWILYNLARHPEYQERCRQEVQELLRDRDSEEIEWDDLAQLPFLT 381

  Fly   364 QVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERF 428
            ..|.|:|||:..|..:.|....|.::|  :...|.||...:|.....|.:..::|:||.::|.||
Mouse   382 MCIKESLRLHPPVLLISRCCTQDVLLP--DGRAIPKGNICVISIFGVHHNPSVWPDPEVYNPFRF 444

  Fly   429 SPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM---S 490
            .||....|..:.::||..|.|||||..|...:.::.||..:.|||:       :|....|.   .
Mouse   445 DPENPQKRSPLAFIPFSAGTRNCIGQTFAMSEIKVALALTLLRFRI-------LPDDKEPRRKPE 502

  Fly   491 IVLGTVGGIYLRVE 504
            ::|...||::||||
Mouse   503 LILRAEGGLWLRVE 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	107/460 (23%)
Cyp4f13	NP_570952.1	CYP4F	74..514	CDD:410772	111/486 (23%)