Protein Alignment Cyp6a2 and Cyp2j6

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_034138.3
• Gene: Cyp2j6 / 13110
• MGIID: 1270148
• Length: 501
• Species: Mus musculus
• Alignment Length: 534
• Identity: 121/534 - (22%)
• Similarity: 211/534 - (39%)
• Gaps: 127/534 - (23%)

  Fly     7 LLIAISSLLAYLYHRN---FNY----WNRR----------GVPHDAPHPL---YGNMVGFRKNRV 51
            |:.|::.||...|.:|   .||    |...          |.||.:..||   |||:.......:
Mouse    22 LVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSLNLGDI 86

  Fly    52 MHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQ 116
            .....         :|.|.:      |.|.    ||:.:||:.:..|...:|....||
Mouse    87 TSVVI---------TGLPLI------KEAL----TQMEQNIMNRPLSVMQERISNKNG------- 125

  Fly   117 HLFNLDGKKWKDMRQRLTPT---FTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKEL 178
             |....|:.||:.|:....|   |..|| |.:...:.:.:...|:.|.|:          |.|..
Mouse   126 -LIFSSGQIWKEQRRFALMTLRNFGLGK-KSLEERMQEEASHLVEAIREE----------EGKPF 178

  Fly   179 MARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKV-FTDMRHGKLLTMF---VFSFPKLASRLR- 238
            ...|:   |......|.|:.         |.|::. :.|.|..::|.:.   ::....:.|:|.
Mouse   179 NPHFS---INNAVSNIICSV---------TFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYN 231

  Fly   239 -----MRMMP----------EDVHQFFMRLVNDTIALRERENF---KRNDFMNLLIE--LKQKGR 283
                 |:.:|          |.:..|...:::|     .|:::   :..||::..::  .|...:
Mouse   232 IFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDD-----HRKDWNPDEPRDFIDAFLKEMTKYPEK 291

  Fly   284 VTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE 348
            .|..|.|        .|.......:.||.||:|:|:.:.|..:|...::|::::.||..|:.::.
Mouse   292 TTSFNEE--------NLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKR 348

  Fly   349 GQLTYESIKAMTYLNQVISETLRLYTLVP-HLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHR 412
            .....:. ::|.|.|.||.|..|:..::| ::.|:...|..:.|..   :.|||.|:....|.||
Mouse   349 AARLADR-ESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFH---LPKGTMVLTNLTALHR 409

  Fly   413 DEDLYPNPETFDPERFSPE-KVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
            |...:..|:.|:||.|... :...|||  :|||..|.|.|:|.:..:.:..|....::.:|
Mouse   410 DPKEWATPDVFNPEHFLENGQFKKRES--FLPFSMGKRACLGEQLARSELFIFFTSLMQKF---- 468

  Fly   477 CDTTEIPL--KYSP 488
              |...|:  |.||
Mouse   469 --TFNPPINEKLSP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	103/452 (23%)
Cyp2j6	NP_034138.3	CYP2J	75..495	CDD:410755	107/481 (22%)