Protein Alignment Cyp6a2 and Cyp2j5

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_034137.1
• Gene: Cyp2j5 / 13109
• MGIID: 1270149
• Length: 501
• Species: Mus musculus
• Alignment Length: 537
• Identity: 119/537 - (22%)
• Similarity: 210/537 - (39%)
• Gaps: 112/537 - (20%)

  Fly     5 IYLLIAISSLLAYLYHRNF-------NY----WNRRGVPHDAPHPLYGNMVGF---RKNRVMHDF 55
            ::|...:.:::.:|:..|.       ||    |..         |..||....   :.:.|:..|
Mouse    16 LHLKTLVLAVVTFLFLINILRSRHPKNYPPGPWRL---------PFVGNFFQIDTKQTHLVLQQF 71

  Fly    56 FYDYYNKYR----------KSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGR 110
            ...|.|.:.          .||.|.:...|.|          |.:|.:.:..:...:|....||
Mouse    72 VKKYGNVFSLELGQSPVVVVSGLPLIKEMFTH----------LDQNFVNRFMTPVRERITGKNG- 125

  Fly   111 DDPLTQHLFNLDGKKWKDMRQRLT----PTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGA 171
                   |...:|:.||:.| ||.    ..|..|| |.:...:.:.:...|:.|.|     :.|.
Mouse   126 -------LVVSNGQTWKEQR-RLALMALRNFGLGK-KSLEERIQEETHHLVEAIRE-----EGGQ 176

  Fly   172 VLEIKELMARFTTDVIGTCAFG-----IEC---NTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVF 228
            .......:....:::|.:..||     .:|   ..|:........||...      |:|..
Mouse   177 PFNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSA------GQLYN---- 231

  Fly   229 SFPKLASRLRMRMMPEDVHQFF-----MRLVNDTIALRERENF---KRNDFMN-LLIEL-KQKGR 283
            .||.:     |:.:|....:.|     ::|....|..:..:::   :..||:: .|||: |...|
Mouse   232 GFPCI-----MKYLPGPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEPRDFIDAFLIEMQKDPDR 291

  Fly   284 VTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE 348
            .|..|.|        .|.:.....::.|.||:|||:.:.|..::...:||:.::.||..|:..:.
Mouse   292 TTSFNEE--------NLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKR 348

  Fly   349 GQLTYESIKAMTYLNQVISETLRLYTLVP-HLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHR 412
             |::....::|.|.|.||.|..|:..:|| :..|:...|....|..   :.|||.::....|.||
Mouse   349 -QVSLSDRESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFH---LPKGTMILTNLTALHR 409

  Fly   413 DEDLYPNPETFDPERFSPE-KVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
            |...:..||.|:||.|... :...|||  :|||..|.|.|:|.:..:.:..|..:.::.:|....
Mouse   410 DPKEWATPEVFNPEHFLENGQFKKRES--FLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKP 472

  Fly   477 CDTTEIPLKYSPMSIVL 493
            ....::.||:. |.::|
Mouse   473 PINEKLSLKFR-MGLIL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	104/449 (23%)
Cyp2j5	NP_034137.1	CYP2J	75..495	CDD:410755	108/469 (23%)