Protein Alignment Cyp6a2 and LOC11175455

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_003436121.2
• Gene: LOC11175455 / 11175455
• VectorBaseID: AGAMI1_000561
• Length: 510
• Species: Anopheles gambiae
• Alignment Length: 555
• Identity: 138/555 - (24%)
• Similarity: 239/555 - (43%)
• Gaps: 100/555 - (18%)

  Fly     1 MFVLIYLLIA-ISSLLAYLYHRNFN----YWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYD-- 58
            |||....|:| |:|:..|:|...|:    :..:.|.|.  .:||.||.:.| ..:...:|...
Mosquito     1 MFVATLTLLALIASVAFYVYVERFSKILKHSGKLGGPR--AYPLIGNGLLF-AGKTPAEFLQTVG 62

  Fly    59 -YYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLD 122
             ...:|.|....::|...|      ||.|:......|...:.:.|:...::.....|.:.|....
Mosquito    63 RLIQQYGKCFRIWLGTQML------IVITEPKDVEAILSSNKYIDKSIEYDFIRPWLGEGLLTST 121

  Fly   123 GKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQ--------VPAAQNGAVLEIKELM 179
            |:||...|:.:||||.           .|:.|:||::..:|        ...|::|...:|...:
Mosquito   122 GRKWHTHRKVITPTFH-----------FKILEQFVEIFDQQSSTFVQVLAAHAKSGDTFDIFRPV 175

  Fly   180 ARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFV-------FSFPKLASRL 237
            .....|||...|.|.:.|......|:: ....|..|::...:|....:       ||    |:|.
Mosquito   176 TLCALDVICETAMGTKVNAQLNTESEY-VQAVKDITNLVQIRLFNFLIRYEIFYRFS----ANRR 235

  Fly   238 RMRMMPEDVHQFFMRLVNDTIALRERENFKR--------------ND--------FMNLLIELKQ 280
            :.....:.:|.:     .|::....||...|              |:        |:::|::.|.
Mosquito   236 KQLEALKVLHGY-----TDSVIKSRREELNRAAGSGKNTVVDENENELGIKKKMAFLDMLLQSKI 295

  Fly   281 KGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVL- 344
            .|:...|.          |:..:|..|...|.:|::|.:|:.|..||::..||.::.:|::.|:
Mosquito   296 DGQPLTDL----------EIREEVDTFMFEGHDTTTSAISFLLQNLAKHPAIQQKVFDEVRNVVG 350

  Fly   345 EEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACA 409
            :::...:|...:..|.||:.||.||||||..||...||.:.|..:.|.   |...|:..||....
Mosquito   351 DDRTRPVTIAMLNDMHYLDLVIKETLRLYPSVPMFGRKMMEDAEINGK---VFPAGSNTIILPFF 412

  Fly   410 YHRDEDLYPNPETFDPERFSPEKVAARES-VEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFR 473
            ..|:.:.:||||.||||||:.|..|.:.: .:::||..|||||||.:|...:.:..:::::..:.
Mosquito   413 LGRNPEFFPNPEKFDPERFNVETSAEKTNPYQYVPFSAGPRNCIGQKFAVAEIKSLVSKLLRNYE 477

  Fly   474 ----VSVCDTTEIPLKYSPMSIVLGTVGGIYLRVE 504
                |...|.|.|      ..::|....|||:|::
Mosquito   478 ILPPVGRYDETFI------AELILRPEKGIYVRLQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	115/473 (24%)
LOC11175455	XP_003436121.2	None