Protein Alignment Cyp6a2 and Cyp4f15

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 554
• Identity: 138/554 - (24%)
• Similarity: 231/554 - (41%)
• Gaps: 102/554 - (18%)

  Fly     4 LIYLLIAISSLLA------YLYHRNFNY---------WN----RRGVPHDAPHPL--YGNMVGFR 47
            |:.|||..|.|||      |:::|.:::         ||    ..|:.....|.|  ..|:|.
Mouse    25 LLLLLIGASWLLARVLTQTYIFYRTYHHLCDFPQPPKWNWFLGHLGMITPTEHGLKEVTNLVA-- 87

  Fly    48 KNRVMHDFFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDD 112
                          .|.:....::|...   |...:....:.:::|....|.......|::....
Mouse    88 --------------TYPQGFMTWLGPII---PIITLCHPDIIRSVLNASASVALKEVVFYSFLKP 135

  Fly   113 PLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITE---------QVPAAQ 168
            .|...|...||.||...|:.|||.|.           ..:.:.:||:..:         |..|:.
Mouse   136 WLGDGLLLSDGDKWSSHRRMLTPAFH-----------FNILKPYVKIFNDSTNIMHAKWQHLASG 189

  Fly   169 NGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDF--RTMGQKVFTDMRHGKLLTMFVFSFP 231
            ..|.|::.|.::..|.|.:..|.|..:.|....| |::  ..:........|:.:||......:.
Mouse   190 GSARLDVFENISLMTLDSLQKCVFSFDSNCQENP-SEYISAILELSALVTKRYHQLLLHIDSLYQ 253

  Fly   232 KLASRLRMRMMPEDVHQFFMRLVND---TI-------ALRERENFKRNDFMNLLIELKQKGRVTL 286
            ...|..|.......||.|...::.|   |:       .|:.:...|..||:::|:..|.
Mouse   254 LTCSGRRFHKACHLVHSFTDAVIQDRRRTLPSKHEDDVLKAKAKSKTLDFIDVLLLSKD------ 312

  Fly   287 DNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQ- 350
            ::|:.:...||   .|:...|...|.:|::|.:|:.||.||::.:.|:|.|.|:|.:|.::|..
Mouse   313 EDGKELSDEDI---RAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRDRESTE 374

  Fly   351 -------LTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPAC 408
                   ...:.:..:.:|...|.|:|||:..|..:.|:...|.|:|  :..||.||...||...
Mouse   375 IECSCAVFLRDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLP--DGRVIPKGVICIINIF 437

  Fly   409 AYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFR 473
            |.|.:..::|:||.:||.||.||.:..|..:.::||..|||||||..|...:.::.||..:.|||
Mouse   438 ATHHNPTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFR 502

  Fly   474 VSVCDTTEIPLKYSPM---SIVLGTVGGIYLRVE 504
            |       :|....|.   .::|...||::||||
Mouse   503 V-------LPDDKEPRRKPELILRAEGGLWLRVE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	116/462 (25%)
Cyp4f15	NP_598888.1	CYP4F	79..527	CDD:410772	120/496 (24%)