Protein Alignment Cyp6a2 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 120/506 - (23%)
• Similarity: 217/506 - (42%)
• Gaps: 85/506 - (16%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNR----VMHDFFYDYYN 61
            :.::|..::|..:..||:.:.:..|.:..|.|.|:  .|.|::....|..    |:||.|..:..
 Frog    18 LLIIIGAVVAFLAYCAYIKYMHLKYDDIPGPPRDS--FLLGHIPTLSKAEENYSVVHDLFLHWAE 80

  Fly    62 KYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLT-QHLFNLDGKK 125
            .|.    |......||:...:....:..|..|:.  |.:.         .||.| ..||||.||:
 Frog    81 IYG----PVFKINILHRVMIYSTSPESVKECLMS--SKYP---------KDPYTYNQLFNLFGKR 130

  Fly   126 --------------WKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIK 176
                          |...|:.:.|.|::..:|.|.....:.:|:.::.:.|:....|.   :.:.
 Frog   131 FLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKADGHQE---VSMH 192

  Fly   177 ELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRM 241
            .::.|.|.|||...|||::...:....:||.....||.|.|.. .:...::..|||
 Frog   193 SIINRVTLDVITKVAFGMDLGLVEGNKTDFPNAISKVLTGMMR-YMQNPYMQYFPK--------- 247

  Fly   242 MPEDVHQFFMRLVNDTI---------ALRERENFKRN------DFMNLLIELKQKGRVTLDNGEV 291
                 |..|:|.|.::.         .:.:|:...:|      |.:..:::..:     |:|
 Frog   248 -----HWAFVREVQESADLLRKTGKECISQRKKAMQNGEELPKDILTKILQCAE-----LEN--- 299

  Fly   292 IEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESI 356
              .:|...:......|::||.||:::.:|:.:.||.:..:|..:||.|:..|:..:. .::|:.|
 Frog   300 --ALDDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKR-DISYDDI 361

  Fly   357 KAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPE 421
            :.:.|:.||:.|:||.|...|...|....|.:..|   :.|..|..:........|.|..:.:|.
 Frog   362 QNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEG---IKIPGGVSITFNTYVMGRMEKFFQDPC 423

  Fly   422 TFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRF 472
            .||||||.|  .|.:....:.||..|||:|:|..|.|::|::.|:::|.||
 Frog   424 KFDPERFHP--AAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRF 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	104/434 (24%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	108/450 (24%)