Protein Alignment Cyp6a2 and cyp4b1.5

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_031756807.1
• Gene: cyp4b1.5 / 100488227
• XenbaseID: XB-GENE-5810927
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 142/545 - (26%)
• Similarity: 232/545 - (42%)
• Gaps: 94/545 - (17%)

  Fly     5 IYLLIAISSLLAYLYHRNFNYWNRRGV-----PHDAP--HPLYGNMVGFRKNRVMHDFF-----Y 57
            :|...|...||..||.....|..||.:     |...|  |.||||         .|:||     .
 Frog    14 LYSWAASLCLLLVLYKATQLYLKRRFLVAALSPFPGPKSHWLYGN---------AHEFFQVGKEL 69

  Fly    58 DYYNKYRKSGFPF-VGFYFLHKPAA-FIVDTQLAKNILIKDFSNFADRGQFHNGRDDP------- 113
            |...::.:. :|: |..:..:..|| |:.....||.||               ||.:|
 Frog    70 DLILRWAQV-YPYGVSMWLGNFHAALFVTHPDYAKAIL---------------GRQEPKDDTAYK 118

  Fly   114 -----LTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQ----VPAAQN 169
                 :.:.|..|.|.||...|:.|||.|....:|    ..:.:..:..:|:.::    :|   |
 Frog   119 YLVPWIGKGLLVLSGPKWFQHRRLLTPGFHYDVLK----QYVSLMSDCTRVMLDKWDKLMP---N 176

  Fly   170 GAVLEIKELMARFTTDVIGTCAFGI--ECNTLRTP--VSDFRTMGQKVFTDMRHGKLLTMFVFSF 230
            ...:|:...::..|.|.|..|||..  .|...|..  :.....:...|:............:||.
 Frog   177 EKSIELFHHVSLMTLDTIMKCAFSYNSSCQNNRDNEYIKAVYELSYLVYERSSFFPYHNDVIFSL 241

  Fly   231 PKLASRLRMRMMPEDVHQFFMR--------LVNDTIALRERENFKRN-DFMNLLIELKQKGRVTL 286
            ..|..|.|..:  ...||...:        |:|:|..  ::.:.||: ||:::|:..|.
 Frog   242 SPLGFRFRKAL--SIAHQHTDKVIKHRKESLINETEL--DKISQKRHLDFLDILLFAKD------ 296

  Fly   287 DNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQL 351
            :||   :|:...:|.|:|..|..||.:|::|.:|:.||.:|:..:.|.:.|.||..:|.::| .:
 Frog   297 ENG---KGLSDEDLRAEVDTFMFAGHDTTASGISWILYCIAKYPEHQQKCREEITELLGDRE-TM 357

  Fly   352 TYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDL 416
            .:..:..:.|....|.|:||||..||.:.|:............|  .:||:||....|.:|...:
 Frog   358 EWGDLGQIPYTTSCIKESLRLYPPVPIIGRRLSKSITFSDGRSL--PEGTEVITSIYAINRSPSV 420

  Fly   417 YPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTE 481
            :.:||.|||.|||||...:|....::||..|||||||..|...:.::.:|..:.|:.: ..|...
 Frog   421 WKDPEVFDPSRFSPENSDSRHPHAFIPFSAGPRNCIGQNFAMNEMKVVVALTLQRYEL-FPDPDN 484

  Fly   482 IPLKYSPMSIVLGTVGGIYLRVERI 506
            .|.|..  .|||.::.||.:::.|:
 Frog   485 KPQKVP--QIVLRSLNGINVKIRRV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	120/461 (26%)
cyp4b1.5	XP_031756807.1	CYP4B-like	69..503	CDD:410771	122/475 (26%)