Protein Alignment Cyp6a2 and cyp4b1.3

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_002931492.1
• Gene: cyp4b1.3 / 100487918
• XenbaseID: XB-GENE-980014
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 546
• Identity: 149/546 - (27%)
• Similarity: 243/546 - (44%)
• Gaps: 100/546 - (18%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNR-----RGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYY 60
            :..||.||:....|        |..|..     :..|....|.||||...||.:....|....:.
 Frog    27 LLCLILLLLKACGL--------FIRWKSLKDALQNFPGPPKHWLYGNANQFRNDGTDMDRILLWA 83

  Fly    61 NKYRKSGFP-FVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLT--------- 115
            |||.|: || :||.:|   .:..|.:.:.||       :.||        |.||.|
 Frog    84 NKYPKA-FPLWVGQFF---ASLVITNPEYAK-------AAFA--------RSDPKTPTGYDFLIP 129

  Fly   116 ---QHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKE 177
               :.|..|.|..|...|:.|||.|....:|   |....:|:....::.:.||.:..|..:|:..
 Frog   130 WIGKGLLVLSGDTWFQHRRLLTPGFHYDVLK---PYAKLISDSTKVMLDKWVPFSNKGEPVELFH 191

  Fly   178 LMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTM--------------FVF 228
            .::..|.|.|..|||....| .:|...:..|......:.:.|.:..|.              |:|
 Frog   192 HVSLMTLDSIMKCAFSYHSN-CQTDNDNSYTKAVYDLSYLTHHRARTFPYHNNLIYYLSPHGFLF 255

  Fly   229 SFPKLASRLRMRMMPEDVHQFFMRLVND-TIALRERENF-----KRN-DFMNLLIELKQKGRVTL 286
               :.|.|:        .||...:::.. ...|:.:|.|     ||: ||:::|:..:.
 Frog   256 ---RKACRI--------AHQHTDKVIKQRKTLLQNKEEFEKVKQKRHPDFLDILLCARD------ 303

  Fly   287 DNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQL 351
            :||   :|:...:|.|:|..|...|.:|::|.:|:.||.:|:..:.|.:.|.||:.||.|:| ..
 Frog   304 ENG---KGLSDEDLRAEVDTFMFEGHDTTASGISWILYCMAKYPEHQQKCREEIRDVLGEKE-SF 364

  Fly   352 TYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVV--PGHEKLVIEKGTQVIIPACAYHRDE 414
            .:|.:..:.|....|.|:||||..||.:.|: ||..:.  .|..   :..|:.:.|.....||:.
 Frog   365 EWEDLNKIPYTTMCIKESLRLYPPVPAVSRE-LNKPITFSDGRS---LPAGSVIFINIFCIHRNP 425

  Fly   415 DLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDT 479
            .::.:||.|||.|||.|..:.|.|..::||..|||||||..|...:.::.:|..::|:.:|. |.
 Frog   426 TVWKDPEVFDPLRFSSENSSKRHSHAFVPFAAGPRNCIGQNFAMNELKVAVALTLNRYELSP-DL 489

  Fly   480 TEIPLKYSPMSIVLGTVGGIYLRVER 505
            ::.||| || .:||.:..||::.:::
 Frog   490 SKAPLK-SP-QLVLRSKNGIHVYLKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	127/466 (27%)
cyp4b1.3	XP_002931492.1	CYP4B-like	76..510	CDD:410771	134/484 (28%)