Protein Alignment Cyp6a2 and Cyp2j11

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001004141.2
• Gene: Cyp2j11 / 100066
• MGIID: 2140224
• Length: 504
• Species: Mus musculus
• Alignment Length: 557
• Identity: 117/557 - (21%)
• Similarity: 209/557 - (37%)
• Gaps: 121/557 - (21%)

  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPH-----PLYGNMVGF-----RKNRVMHDF 55
            ::.|:..|:.:..|..||.       |||  |.:.|.     |..||:..|     |.:..:..|
Mouse    18 LWTLLLTLLTLLLLADYLK-------NRR--PKNYPPGPRRLPFVGNLFQFDLDVSRLHLGIQPF 73

  Fly    56 FYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFN 120
            ...|.|        .:...|.:..:..|....|.|..:.....||..|...      ...||:|.
Mouse    74 VKKYGN--------VISVNFGYISSVIISGLPLIKEAITGMEQNFLKRPSL------AARQHVFK 124

  Fly   121 ------LDGKKWKDMRQ---RLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIK 176
                  ..|:.||:.|:   .:...|..|| |.:...:.:.:...||.|.|     :.|...:..
Mouse   125 NNGIVFSSGQTWKEQRKFALTILKNFGLGK-KSLEQCIQEEAYHLVKAIGE-----EKGQPFDPH 183

  Fly   177 ELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRM 241
            ..:.....::|.:..||...........:...:..::...  ...::::....||.:     .:.
Mouse   184 FRINNAVGNIICSIIFGERFEYDDNQFQELLKLADEIICS--EASMMSVLYNVFPSI-----FKY 241

  Fly   242 MP----------EDVHQFFMRLVNDTIALRERENFKRN---DFMN-LLIEL-KQKGRVTLDNGE- 290
            :|          |.:..|..|:::.     .||::..:   ||:: .|.|: |...:.|....|
Mouse   242 LPGPQQKLFSNWEKLKLFVSRMMDS-----HREDWNPSAPRDFIDAFLTEMTKYPDKTTTSFNEE 301

  Fly   291 --VIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTV--------LE 345
              :...:|:          :.||.||:|:|:.:.|..:..|.::|:::.:||..|        |:
Mouse   302 NLICTALDL----------FFAGTETTSNTLRWALLYITVNPEVQEKVHSEIDRVIGHGRHPTLD 356

  Fly   346 EQEGQLTYESIKAMTYLNQVISETLRLYTLVP-HLERKALNDYVVPGHEKLVIEKGTQVIIPACA 409
            :|:         :|.|.|.||.|.||:..::| ::.|:...|..:.|   ..:.|||.|:|....
Mouse   357 DQD---------SMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAG---FYLPKGTMVLINLTD 409

  Fly   410 YHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRV 474
            .|||...:..|..|:||.|. |....::...:|||..|.|.|.|.:....:..|....::.:|
Mouse   410 LHRDPKEWDTPNVFNPEHFL-ENGQFKKKESFLPFSMGKRACPGEQLASCELFIFFTALMQKF-- 471

  Fly   475 SVCDTTEIPLKYSP-----MSIVLGTVGGIYLRVERI 506
                |.:.|:...|     |.:.|..|......|.|:
Mouse   472 ----TFKSPINEKPSLKFRMGLTLAPVSYRICAVPRL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	97/471 (21%)
Cyp2j11	NP_001004141.2	cytochrome_P450	77..498	CDD:477761	99/481 (21%)