Protein Alignment Cyp6a2 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 500
• Identity: 168/500 - (33%)
• Similarity: 265/500 - (53%)
• Gaps: 40/500 - (8%)

  Fly     6 YLLIAISSLLAYLY-HRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKSGFP 69
            ::|:||..:|.|.| .|....:.::|:|...|.|..|.::.:.|.  :..|..:.|.||.|:...
Mouse    12 WVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKG--LWKFDMECYEKYGKTWGL 74

  Fly    70 FVGFYFLHKPAAFIVDTQLAKNILIKD-FSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRL 133
            |.|    ..|...|.|.::.||:|:|: ||.|.:|.:|  |....:::.:.....::||..|..|
Mouse    75 FDG----QMPLFVITDPEMIKNVLVKECFSVFTNRREF--GPVGIMSKAISISKDEEWKRYRALL 133

  Fly   134 TPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNT 198
            :|||||||:|.|||.:.:..:..||.:.::   |:.|..:.:|:::..::.|||.:.:||:..::
Mouse   134 SPTFTSGKLKEMFPVIEQYGDILVKYLMQE---AEKGKPVTMKDVLGAYSIDVITSTSFGVNVDS 195

  Fly   199 LRTPVSDFRTMGQKVFTDMRHGKLLTMF----VFS---FPKLA---SRLRMRMMPEDVHQFFMRL 253
            |..|        :..|.:...|.|...|    |||   ||.|.   ..|.:.|.|:|..:||.:.
Mouse   196 LNNP--------EDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKF 252

  Fly   254 VNDTIALR-ERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSS 317
            ||.....| :.:...|.||:.|::......: ..|:.:.:..|   |:.||..||..||:||:||
Mouse   253 VNRMKESRLDSKQKHRVDFLQLMMNAHNNSK-DKDSHKALSDM---EITAQSIVFIFAGYETTSS 313

  Fly   318 TMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERK 382
            |:|:.||.||.:.|||.:|:.||...| ..:...||:::..|.||:.|::||||||.:...|||.
Mouse   314 TLSFTLYCLATHPDIQKKLQEEIDETL-PNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERF 377

  Fly   383 ALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDG 447
            ...|..:.|   :.|.||:.|:||:.|.|.|...:|.||.|.|||||.|...:.:...::|||.|
Mouse   378 CKKDVELNG---VYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIG 439

  Fly   448 PRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIV 492
            |||||||||..|..::.|.:::..|....|..|:||||.|...::
Mouse   440 PRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	150/435 (34%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	153/442 (35%)