Protein Alignment CG9436 and AKR1D1

DIOPT Version :9

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 130/321 - (40%)
• Similarity: 184/321 - (57%)
• Gaps: 21/321 - (6%)

  Fly     8 IRLNNGREMPTLGLGTWKSFESD----AYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68
            |.|::|..:|.:||||:...:|.    ...|.:.|:|.||||:|.|::|:||.|||:||.|||||
Human    10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAE 74

  Fly    69 GVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK-----FHNDSNVH 128
            |.|.||::|...||...:|.|.:|......:|..|.|:|||||::.:|:..|     :..|.|
Human    75 GKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDEN-- 137

  Fly   129 GTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGFQQ 191
            |.......:...||..||...|.||.:|:|:||||..|.|.:|  ...:.:||.|||||||.|.|
Human   138 GKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQ 202

  Fly   192 RQLREHAKRHGLVICAYCPLARPQ-PARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQ 250
            .:|.:..::|.:||.||.||...: |.  |     ||.|.|....:|.|:|.:|.|||.||:.:|
Human   203 PKLLKFCQQHDIVITAYSPLGTSRNPI--WVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQ 265

  Fly   251 LGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFNDEF 311
            .|||.:|||.|..||:|||::|||.|:.:::..:|..:...|.|.......|..|||:||:
Human   266 RGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	124/306 (41%)
		Tas	6..282	CDD:223739	121/290 (42%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	124/310 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.760