Protein Alignment CG9436 and Akr1a1

DIOPT Version :10

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_067448.1
• Gene: Akr1a1 / 58810
• MGIID: 1929955
• Length: 325
• Species: Mus musculus
• Alignment Length: 323
• Identity: 137/323 - (42%)
• Similarity: 191/323 - (59%)
• Gaps: 16/323 - (4%)

  Fly     5 APTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEG 69
            |.::.|:.|::||.:|||||||.......:.:|||..||||:|.|.||.||.|:|:|:.|.:..|
Mouse     3 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSG 67

  Fly    70 -VVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG-QKFHN--DSNVHGT 130
             .|.|||:|||:||....|.|..||.|.|.:|::|.|||:||||||.|.. ::..|  ..|..||
Mouse    68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGT 132

  Fly   131 LELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLR 195
            :......|.:||:.:|.||..||.:::||||||:.|.:.||:...:||.|.||||||...|.:|.
Mouse   133 VRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELI 197

  Fly   196 EHAKRHGLVICAYCPLARPQPARQWP--PFLYDEH-AQNLAKKYGRTTAQICLRYLVQLGVVPLP 257
            .|....||.:.||.||.....|.:.|  |.|.:|. ...||:|:||:.|||.||:.||..|:.:|
Mouse   198 AHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIP 262

  Fly   258 KSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQR-TVPFSGM--------SGHKYYPFNDEF 311
            ||.|.:||.:|.:||||..||:::..::..:...| .||...:        :||..|||||.:
Mouse   263 KSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFNDPY 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	AKR_AKR2E1-5	6..294	CDD:381342	127/295 (43%)
Akr1a1	NP_067448.1	AKR_AKR1A1-4	8..312	CDD:381332	129/303 (43%)