Protein Alignment CG9436 and AKR1B10

DIOPT Version :10

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_064695.3
• Gene: AKR1B10 / 57016
• HGNCID: 382
• Length: 316
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 124/322 - (38%)
• Similarity: 184/322 - (57%)
• Gaps: 20/322 - (6%)

  Fly     4 LAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68
            :|..:.|:...:||.:|||||||.......:.:.|:|.||||:|.|:||:||.|||:||.|||.|
Human     1 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQE 65

  Fly    69 GVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND-------SN 126
            ..|.||::|:.:||.....:..||.:|...:|.:|.|.|:|:||:|.|.|.|..:|       .|
Human    66 KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGN 130

  Fly   127 VHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGF 189
            ..|    ....:||.|..||:|||.||.:::|:|||:..|.|::|  ...:.:||.|||||||..
Human   131 AIG----GKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYL 191

  Fly   190 QQRQLREHAKRHGLVICAYCPLARPQPARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLV 249
            .|.:|.::....|:.:.||.||..|.  |.|     |..|.|...:.:|.|:.:|.||:.:|:.:
Human   192 TQEKLIQYCHSKGITVTAYSPLGSPD--RPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHI 254

  Fly   250 QLGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFNDEF 311
            |..|:.:|||...|||.||.:||||:||.:::|.:..::...|.......|..:.||||.|:
Human   255 QRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFNAEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	AKR_AKR2E1-5	6..294	CDD:381342	117/301 (39%)
AKR1B10	NP_064695.3	AKR_AKR1B1-19	10..316	CDD:381333	121/311 (39%)