DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9436 and akr1b1

DIOPT Version :9

Sequence 1:	NP_610235.1	Gene:	CG9436 / 35586	FlyBaseID:	FBgn0033101	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001011130.1	Gene:	akr1b1 / 496546	XenbaseID:	XB-GENE-5821742	Length:	318	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	139/316 - (43%)
Similarity:	199/316 - (62%)	Gaps:	17/316 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PT-IRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEG 69
            || ::|..|.:||.:|||||||.......:...|::|||||||.|:||:||.|||:.|.:||.||
Frog     4 PTHVQLYTGAQMPIVGLGTWKSEPGKVTAAVAKAIEVGYRHLDCAYVYQNENEVGEGIQQKIKEG 68

  Fly    70 VVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK-----FHNDSNVHG 129
            :|.||::||.:||....||.::|:.||:.:||:|.|:|:||||:|.|.|.:     |..|:  .|
Frog    69 LVKREDLFVVSKLWSTFHDKSMVKGACQKTLSDLKLDYLDLYLVHWPTGFQAGDALFPLDN--EG 131

  Fly   130 TLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGFQQR 192
            .:..::..:||||..||:|||.||.::||:||||..|.|::|  ...:.:|.|:|.||||...|:
Frog   132 CVIHSNTHFLDTWEGMEELVDAGLVKAIGISNFNREQIEQLLNKPGLKHKPAVHQFECHPYLTQK 196

  Fly   193 QLREHAKRHGLVICAYCPLARPQPARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQLG 252
            :|.:..:..|:|:.||.||..|.  |.|     |..|.:...:.:||||.:|:||:.:|:.:|..
Frog   197 KLIDLCQSKGIVVTAYSPLGSPD--RPWAKPEDPSLLEEPKIKEIAKKYNKTSAQVLIRFHIQRN 259

  Fly   253 VVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFN 308
            ||.:|||...|||||||:||||||||:|...:..:..|.|....|....||.|||:
Frog   260 VVVIPKSVTPARIEENFQVFDFELSPEDTEAIFSFERGWRVCALSSAKKHKDYPFH 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	133/304 (44%)
CG9436	NP_610235.1	Tas	6..282	CDD:223739	131/288 (45%)
akr1b1	NP_001011130.1	AKR_AKR1B1-19	12..318	CDD:381333	136/308 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040