Protein Alignment CG9436 and AKR1B15

DIOPT Version :10

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001074007.2
• Gene: AKR1B15 / 441282
• HGNCID: 37281
• Length: 344
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 117/320 - (36%)
• Similarity: 176/320 - (55%)
• Gaps: 24/320 - (7%)

  Fly     2 TNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKI 66
            |:..|.:     |..|...||..|       .:.:.|:|..|||:|.|:.|||:.|||:||.|||
Human    39 TSAGPLL-----RPYPASLLGKVK-------EAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKI 91

  Fly    67 AEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND---SNVH 128
            .|..|.||::|:.:|:.....:..||.:|...:|.:|.|.|:|:||:|.|.|.|..:|   .:..
Human    92 QEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDK 156

  Fly   129 GTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGFQQ 191
            |.:......:||.|..||:|||.||.:::|:||||..|.||:|  ...:.:||.|||||||...|
Human   157 GNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQ 221

  Fly   192 RQLREHAKRHGLVICAYCPLARPQPARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQL 251
            .:|.::....|:.:.||.||..|.  |.|     |..|.|...:.:|.|:.:||||:.:|:.:|.
Human   222 EKLIQYCHSKGITVTAYSPLGSPD--RPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQR 284

  Fly   252 GVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFNDEF 311
            .|..:|||...|.|.||.:||||:||.:::|.:..::...|...|...|..:.:||:.|:
Human   285 NVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFDAEY 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	AKR_AKR2E1-5	6..294	CDD:381342	111/297 (37%)
AKR1B15	NP_001074007.2	AKR_AKR1B1-19	51..344	CDD:381333	112/301 (37%)