DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9436 and Akr1b10

DIOPT Version :9

Sequence 1:	NP_610235.1	Gene:	CG9436 / 35586	FlyBaseID:	FBgn0033101	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001013102.1	Gene:	Akr1b10 / 296972	RGDID:	1308277	Length:	316	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	121/316 - (38%)
Similarity:	192/316 - (60%)	Gaps:	8/316 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68
            :|..::|:...:||.:|||||||.......:.:.|:|.||||.|.|:||:||:|||:||.|||.|
  Rat     1 MAAFVKLSTKAKMPIVGLGTWKSPPDKVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKE 65

  Fly    69 GVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHN---DSNVHGT 130
            ..|.||::|:.:||.....:.:||::|.:.:|.:|.|:|:||||:|.|.|.:..|   .::..|.
  Rat    66 KAVRREDLFIVSKLWPTFFEKSLVKKAFQKTLLDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGN 130

  Fly   131 LELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGFQQRQ 193
            :..:...:||.|..||:|||.||.:::|:||||..|.||:|  ...:.:||.|||||||...|.:
  Rat   131 VLTSKYTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEK 195

  Fly   194 LREHAKRHGLVICAYCPLA---RPQPARQWPPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVP 255
            |.::....|:|:.||.||.   ||....:.|..|.....:.:|.|:.:|.||:.:|:.::..|..
  Rat   196 LIQYCHSKGIVVTAYSPLGSPDRPSAKPEDPVLLEIPKIKEIASKHKKTAAQVLIRFHIERNVAV 260

  Fly   256 LPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFNDEF 311
            :|||...:||:||.:||||:||.:|:|.:..::...|.......|.::.:||:.|:
  Rat   261 IPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWRACGLFAASRNEDFPFHSEY 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	117/301 (39%)
CG9436	NP_610235.1	Tas	6..282	CDD:223739	114/283 (40%)
Akr1b10	NP_001013102.1	AKR_AKR1B1-19	10..316	CDD:381333	118/305 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730