DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9436 and SPBC8E4.04

DIOPT Version :9

Sequence 1:	NP_610235.1	Gene:	CG9436 / 35586	FlyBaseID:	FBgn0033101	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_596843.1	Gene:	SPBC8E4.04 / 2541256	PomBaseID:	SPBC8E4.04	Length:	325	Species:	Schizosaccharomyces pombe

Alignment Length:	274	Identity:	100/274 - (36%)
Similarity:	145/274 - (52%)	Gaps:	25/274 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEGVVTRE 74
            |.||.::|::|||||:|.:.:..::...||..||||:|||.:|.||.|:|    |.|.|..|.|.
pombe    17 LPNGDKIPSIGLGTWRSGKDETKNAVCAALKAGYRHIDTAHIYGNEKEIG----EGIRESGVPRT 77

  Fly    75 EVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDS---NVHGTLELTDV 136
            :::||:||....|...||..|...:|.:|.|||:|.||:|.|.......:.   |..|.|...||
pombe    78 DIWVTSKLWCNAHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFALLSGPEELPRNEKGELIYEDV 142

  Fly   137 DYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRH 201
            ...:||:.||:|::.|..|.||:||||....:|||...:::|.::|:|.||...|.:..|..|:.
pombe   143 PIEETWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAKVKPTIHQMELHPYLPQTEYLEKHKKL 207

  Fly   202 GLVICAYCPLARPQPARQWPPFLYDEHAQNL-----------AKKYGRTTAQICLRYLVQLGVVP 255
            .:.:.||.|||....|       |:.....|           |:..|.|.|.|.:.:.|:.|...
pombe   208 QIHVSAYSPLANQNDA-------YNSDISKLIEHKTLVDIANARGEGITPANIAISWAVKRGTSV 265

  Fly   256 LPKSSNKARIEENF 269
            ||||.|::||..||
pombe   266 LPKSVNESRIVSNF 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	100/274 (36%)
CG9436	NP_610235.1	Tas	6..282	CDD:223739	100/274 (36%)
SPBC8E4.04	NP_596843.1	ARA1	12..314	CDD:223729	100/274 (36%)
SPBC8E4.04	NP_596843.1	Tas	13..293	CDD:223739	100/274 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm9270
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
TreeFam	0	0.000	Not matched by this tool.
	9	8.750