Protein Alignment CG9436 and AKR7L

DIOPT Version :10

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001335350.1
• Gene: AKR7L / 246181
• HGNCID: 24056
• Length: 331
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 76/300 - (25%)
• Similarity: 103/300 - (34%)
• Gaps: 94/300 - (31%)

  Fly    35 TRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEGVVTRE-----EVFVTTKLG---GIHHDPAL 91
            ||..|:.|:..:||||:|.:    ||  ||.|..|:..|.     .|.:.||..   |....|..
Human    32 TRAFLERGHTEIDTAFLYSD----GQ--SETILGGLGLRMGSSDCRVKIATKANPWIGNSLKPDS 90

  Fly    92 VERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRS 156
            |......||..|....|||:.:|.|     .:.:.|..||           |...:|...|....
Human    91 VRSQLETSLKRLQCPRVDLFYLHAP-----DHSAPVEETL-----------RACHQLHQEGKFVE 139

  Fly   157 IGLSNFNAAQTERVLANCR----IRPVVNQVECHPGFQQRQLRE------HAKRH-GLVICAYCP 210
            :||||:.|.:...:...|:    |.|.|.|     |......|:      ...|| ||...||.|
Human   140 LGLSNYAAWEVAEICTLCKSNGWILPTVYQ-----GMYSATTRQVETELFPCLRHFGLRFYAYNP 199

  Fly   211 LA--------------RPQP-----ARQWPP-----FLYDEHAQNLA-------KKYGRTTAQI- 243
            ||              ..||     ..||..     |..:.|.:.:|       ..||.:...:
Human   200 LAGGLLTGKYKYEDKDGKQPVGRFFGTQWAEIYRNHFWKEHHFEGIALVEKALQAAYGASAPSMT 264

  Fly   244 --CLRYL-------------VQLGVVPLPK-SSNKARIEE 267
              .||::             |.||:..|.: ..|.|..||
Human   265 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEE 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	AKR_AKR2E1-5	6..294	CDD:381342	75/299 (25%)
AKR7L	NP_001335350.1	AKR_AKR7A1-5	10..319	CDD:381301	75/299 (25%)