Protein Alignment CG9436 and AKR7A3

DIOPT Version :10

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: XP_011539348.1
• Gene: AKR7A3 / 22977
• HGNCID: 390
• Length: 375
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 63/232 - (27%)
• Similarity: 92/232 - (39%)
• Gaps: 55/232 - (23%)

  Fly    35 TRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEGVVTRE-----EVFVTTK---LGGIHHDPAL 91
            ||..|:.|:..:||||||..    ||  ||.|..|:..|.     .|.:.||   |.|....|..
Human    32 TRAFLERGHTEIDTAFVYSE----GQ--SETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDS 90

  Fly    92 VERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRS 156
            :......||..|....|||:.:|||       |.:       |.|:  :|.|...:|...|....
Human    91 LRFQLETSLKRLQCPRVDLFYLHMP-------DHS-------TPVE--ETLRACHQLHQEGKFVE 139

  Fly   157 IGLSNFNAAQTERVLANCR----IRPVV---------NQVECHPGFQQRQLREHAKRHGLVICAY 208
            :||||:.|.:...:...|:    |.|.|         .|||       .:|....:..||...|:
Human   140 LGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE-------TELFPCLRHFGLRFYAF 197

  Fly   209 CPLARPQPARQWPPFLYDEH--AQNLAKKYGRTTAQI 243
            .|||......:   :.|::.  .|.:.:.:|.|.|::
Human   198 NPLAGGLLTGK---YKYEDKNGKQPVGRFFGNTWAEM 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	AKR_AKR2E1-5	6..294	CDD:381342	63/232 (27%)
AKR7A3	XP_011539348.1	AKR_AKR7A1-5	10..281	CDD:381301	63/232 (27%)