Protein Alignment CG9436 and AKR1C1

DIOPT Version :9

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001344.2
• Gene: AKR1C1 / 1645
• HGNCID: 384
• Length: 323
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 136/321 - (42%)
• Similarity: 185/321 - (57%)
• Gaps: 22/321 - (6%)

  Fly     8 IRLNNGREMPTLGLGTWKSFE---SDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEG 69
            ::||:|..||.||.||:...|   |.|..:|:.|::.|:||:|:|.:|.||.:||.||..|||:|
Human     8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADG 72

  Fly    70 VVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK-----FHNDSNVHG 129
            .|.||::|.|:||....|.|.||..|...||.||.|:||||||:|.||..|     ...|.|  |
Human    73 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDEN--G 135

  Fly   130 TLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVL--ANCRIRPVVNQVECHPGFQQR 192
            .:....||...||..:||..|.||.:|||:||||..|.|.:|  ...:.:||.|||||||.|.||
Human   136 KILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQR 200

  Fly   193 QLREHAKRHGLVICAYCPLA--RPQPARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQ 250
            :|.:..|...:|:.||..|.  |.:|   |     |..|.|.....||||:.||.|.|.|||.:|
Human   201 KLLDFCKSKDIVLVAYSALGSHREEP---WVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQ 262

  Fly   251 LGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPFNDEF 311
            .|||.|.||.|:.||.:|.:||:|:|:.:::..::..:...|.:.....:|...|||:||:
Human   263 RGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	130/306 (42%)
		Tas	6..282	CDD:223739	129/290 (44%)
AKR1C1	NP_001344.2	AKR_AKR1C1-35	6..308	CDD:381334	130/304 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1194
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.680