Protein Alignment CG9436 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_610235.1
• Gene: CG9436 / 35586
• FlyBaseID: FBgn0033101
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 134/325 - (41%)
• Similarity: 188/325 - (57%)
• Gaps: 20/325 - (6%)

  Fly     5 APTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAEG 69
            |..:.|:.|::||.:|||||||.......:.::||.|||||:|.|.:|.||.|:|:|:.|.:..|
Human     3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67

  Fly    70 -VVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG-QKFHN--DSNVHGT 130
             .|.|||:|||:||....|.|..||.|.|.:|::|.|||:||||||.|.. ::..|  ..|..||
Human    68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGT 132

  Fly   131 LELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLR 195
            :......|.:||:.:|.||..||.:::||||||:.|.:.:|:...:||.|.||||||...|.:|.
Human   133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELI 197

  Fly   196 EHAKRHGLVICAYCPLARPQPARQW-----PPFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVP 255
            .|.:..||.:.||.||....  |.|     |..|.:.....||:||||:.|||.||:.||..|:.
Human   198 AHCQARGLEVTAYSPLGSSD--RAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVIC 260

  Fly   256 LPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQR-TVPFSGM--------SGHKYYPFNDEF 311
            :|||...:||.:|.:||||..||:::..:...:...| .||...:        :||..|||||.:
Human   261 IPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325

  Fly   312  311
            Human   326  325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9436	NP_610235.1	ARA1	3..298	CDD:223729	127/302 (42%)
		Tas	6..282	CDD:223739	123/284 (43%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	126/298 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.720